CAS 13389-16-7

8-amino-9-pentofuranosyl-3,9-dihydro-6H-purin-6-one

Description:

8-Amino-9-pentofuranosyl-3,9-dihydro-6H-purin-6-one, with the CAS number 13389-16-7, is a purine derivative that exhibits characteristics typical of nucleobases and nucleosides. This compound features an amino group at the 8-position and a pentofuranosyl moiety, which is indicative of its role in nucleic acid structures. The presence of the furanosyl sugar suggests that it can participate in glycosidic bonding, making it relevant in the context of nucleic acid synthesis and metabolism. The dihydro form indicates that it may exist in a reduced state, which can influence its reactivity and stability. This compound is likely to be soluble in polar solvents due to its functional groups, and it may exhibit biological activity, potentially acting as a precursor or intermediate in the synthesis of nucleotides or nucleic acids. Its structural features suggest that it could be involved in various biochemical pathways, particularly those related to cellular energy transfer and genetic information processing.

Formula: C₁₀H₁₃N₅O₅

InChI: InChI=1/C10H13N5O5/c11-10-14-4-7(12-2-13-8(4)19)15(10)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H2,11,14)(H,12,13,19)

SMILES: C(C1C(C(C(n2c3c(c(ncn3)O)[nH]c2=N)O1)O)O)O

8-Amino-Inosine

Controlled Product

CAS: 13389-16-7

Applications 8-Amino-Inosine is an derivative of Inosine (I661000), a nucleoside that is found in tRNAs and is essential for the proper translation of genetic code in a wobble base pair. Inosine is also known to exert neuroprotective properties and has been used to treat stroke patients to restore neural function. 8-Amino-Inosine have been studied as a potential chemotherapeutic agent for the treatment of leukemia function by the cytodestruction of the neoplastic cells.
References Vandemeulebroucke A, et al. 2010. Biochemistry. 2010 Oct 19;49(41):8999-9010Nestor G, et al. 2010. J Agric Food Chem. 2010 Oct 27;58(20):10799-803 Lin TS, et al. 1985. J Med Chem. 1985 Oct;28(10):1481-5.

Formula: C₁₀H₁₃N₅O₅

Color and Shape: Neat

Molecular weight: 283.24

Ref: TR-A611855

8-Aminoinosine

CAS: 13389-16-7

8-Aminoinosine is an endogenous 8-aminopurine that induces diuresis, natriuresis, and glucosuria by inhibiting purine nucleoside phosphorylase (PNPase).

Formula: C₁₀H₁₃N₅O₅

Color and Shape: Solid

Molecular weight: 283.24

Ref: TM-T70939