CAS 133914-58-6

cytorhodin X

Description:

Cytorhodin X, identified by its CAS number 133914-58-6, is a synthetic compound that belongs to the class of cytotoxic agents. It is primarily characterized by its ability to intercalate into DNA, which disrupts the replication and transcription processes, making it a potential candidate for cancer treatment. The compound exhibits a distinct color, typically associated with its chromophore structure, which contributes to its optical properties. Cytorhodin X is known for its moderate solubility in organic solvents and limited solubility in water, which can influence its bioavailability and therapeutic efficacy. Additionally, it may possess various functional groups that contribute to its reactivity and interaction with biological molecules. As with many cytotoxic agents, safety and handling precautions are essential due to its potential toxicity. Research continues to explore its mechanisms of action, efficacy, and potential side effects in clinical applications.

Formula: C₄₈H₆₈N₂O₁₅

InChI: InChI=1/C48H68N2O15/c1-10-48(65-37-18-28(49(6)7)42(53)24(4)60-37)20-27-39(46(57)40-41(44(27)55)45(56)38-26(43(40)54)12-11-13-31(38)52)33(21-48)63-36-19-29(50(8)9)47(25(5)61-36)64-35-17-15-32(23(3)59-35)62-34-16-14-30(51)22(2)58-34/h11-13,22-25,28-30,32-37,42,47,51-53,55,57H,10,14-21H2,1-9H3

Synonyms:

• Cytorhodin A, 7-de[[2,3,6-trideoxy-3-(dimethylamino)-4-O-[[2S-[2α,5β(2R*,5R*,6R*),6β]]-tetrahydro-6-methyl-5-[(tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)oxy]-2H-pyran-2-yl]-α-L-lyxo-hexopyranosyl]oxy]-9-O-[2,3,6-trideoxy-3-(dimethylamino)-α-L-lyxo-hexopyranosyl]- (9CI)
• Cytorhodin A, 7-de((2,3,6-trideoxy-3-(dimethylamino)-4-O-((2S-(2alpha,5beta(2R*,5R*,6R*),6beta))-tetrahydro-6-methyl-5-((tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)oxy)-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)oxy)-9-O-(2,3,6-trideoxy-3-(dimethyamino)-alpha-L-lyxo-hexopyranosyl)-
• cytorhodin X
• Cytorhodin A, 7-de((2,3,6-trideoxy-3-(dimethylamino)-4-O-((2S-(2-alpha,5-beta(2R*,5R*,6R*), 6-beta))-tetrahydro-6-methyl-5-((tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)oxy)-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)oxy)-9-O-(2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)-
• 3-ethyl-5,7,12-trihydroxy-6,11-dioxo-3-{[2,3,6-trideoxy-3-(dimethylamino)hexopyranosyl]oxy}-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-3-(dimethylamino)-4-O-{5-[(5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy]-6-methyltetrahydro-2H-pyran-2-yl}hexopyranoside
• Cytorhodin X

Cytorhodin X

CAS: 133914-58-6

Cytorhodin X is a cytotoxic antibiotic that inhibits the proliferation of L1210 murine leukemia cells, with an ED50 of 0.36 μM.

Formula: C₄₈H₆₈N₂O₁₅

Color and Shape: Solid

Molecular weight: 913.058

Ref: TM-TN9901