CAS 133941-75-0: (3S,4S,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-3-[(1E)-2-[(1R,3R,4R)-4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxycyclohexyl]-1-methylethenyl]-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-19-hydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone

Description: The chemical substance with the name provided is a complex organic compound characterized by its intricate molecular structure, which includes multiple stereocenters and functional groups. It features a hexadecahydro framework, indicating a saturated cyclic structure with numerous hydrogen atoms. The presence of methoxy groups suggests potential reactivity and solubility in organic solvents. The compound also contains silyl ether functionalities, which enhance its stability and may influence its physical properties, such as volatility and solubility. Additionally, the presence of an epoxy group indicates potential for further chemical reactivity, particularly in nucleophilic addition reactions. The stereochemistry, denoted by the specific configuration at various chiral centers, plays a crucial role in determining the compound's biological activity and interaction with biological systems. Overall, this substance exemplifies the complexity often found in natural products and synthetic organic compounds, highlighting the interplay between structure and function in chemical behavior.

Formula: C₅₆H₉₇NO₁₂Si₂

InChI: InChI=1S/C56H97NO12Si2/c1-20-23-41-29-35(2)28-36(3)30-47(64-14)50-48(65-15)32-38(5)56(62,67-50)51(59)52(60)57-27-22-21-24-42(57)53(61)66-49(39(6)45(34-43(41)58)69-71(18,19)55(10,11)12)37(4)31-40-25-26-44(46(33-40)63-13)68-70(16,17)54(7,8)9/h20,29,31,36,38-42,44-50,62H,1,21-28,30,32-34H2,2-19H3/b35-29+,37-31+/t36-,38+,39+,40-,41+,42-,44+,45-,46+,47-,48-,49+,50+,56+/m0/s1

InChI key: InChIKey=ZMQPVYFWZQHALN-SWHZMJOBSA-N

SMILES: O=C1OC(C(=CC2CCC(O[Si](C)(C)C(C)(C)C)C(OC)C2)C)C(C)C(O[Si](C)(C)C(C)(C)C)CC(=O)C(C=C(C)CC(C)CC(OC)C3OC(O)(C(=O)C(=O)N4CCCCC14)C(C)CC3OC)CC=C

Synonyms:

• (3S,4S,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-3-[(1E)-2-[(1R,3R,4R)-4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxycyclohexyl]-1-methylethenyl]-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-19-hydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone
• 24,32-Bis-O-(tert-butyldimethylsilyl)-FK 506
• 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-[(1E)-2-[(1R,3R,4R)-4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxycyclohexyl]-1-methylethenyl]-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-19-hydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-, (3S,4S,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-
• 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-[2-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxycyclohexyl]-1-methylethenyl]-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-19-hydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-, [3S-[3R*[E(1S*,3S*,4S*)],4R*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-
• FK 506 24,32-bis(tert-butyldimethylsilyl) ether

Tacrolimus Impurity 16

CAS: 133941-75-0

• Formula: C₅₆H₉₇NO₁₂Si₂
• Molecular weight: 1032.56

24,32-Bis-O-(tert-butyldimethylsilyl)-FK-506

CAS: 133941-75-0

Applications Protected form of FK-506 (Tacrolimus) References Rokaw, M.D., et al.: Am. J. Physiol., 271, …

• Formula: C₅₆H₉₇NO₁₂Si₂
• Color and Shape: Neat
• Molecular weight: 1032.54

24,32-Bis-O-(tert-butyldimethylsilyl)-FK-506

CAS: 133941-75-0

Please enquire for more information about 24,32-Bis-O-(tert-butyldimethylsilyl)-FK-506 including the price, delivery time and more detailed …

• Formula: C₅₆H₉₇NO₁₂Si₂
• Purity: Min. 95%
• Molecular weight: 1,032.54 g/mol