CAS 134-19-0

2-Methoxy-5-methyl-4-nitrobenzenamine

Description:

2-Methoxy-5-methyl-4-nitrobenzenamine, also known by its CAS number 134-19-0, is an organic compound characterized by its aromatic structure, which includes a methoxy group (-OCH3), a methyl group (-CH3), and a nitro group (-NO2) attached to a benzene ring. This compound typically appears as a solid at room temperature and is soluble in organic solvents. Its molecular structure contributes to its chemical reactivity, particularly in electrophilic substitution reactions due to the presence of the electron-donating methoxy and methyl groups, which can influence the position of further substitutions on the aromatic ring. The nitro group, being electron-withdrawing, can affect the compound's overall reactivity and stability. 2-Methoxy-5-methyl-4-nitrobenzenamine is often used in organic synthesis and may serve as an intermediate in the production of dyes, pharmaceuticals, or other chemical products. Safety data should be consulted for handling and potential hazards associated with this compound.

Formula: C₈H₁₀N₂O₃

InChI: InChI=1S/C8H10N2O3/c1-5-3-6(9)8(13-2)4-7(5)10(11)12/h3-4H,9H2,1-2H3

InChI key: InChIKey=VXUMJWGCPAUKTB-UHFFFAOYSA-N

SMILES: N(=O)(=O)C1=C(C)C=C(N)C(OC)=C1

Synonyms:

• 2-Methoxy-4-nitro-5-methylaniline
• 2-Methoxy-5-methyl-4-nitroaniline
• 2-Methoxy-5-methyl-4-nitrobenzenamine
• 3-Amino-4-methoxy-6-nitrotoluene
• 4-Nitro-p-cresidine
• 5-Amino-4-methoxy-2-nitrotoluene
• 6-Nitro-4-methoxy-3-aminotoluene
• Benzenamine, 2-methoxy-5-methyl-4-nitro-
• Nsc 50663
• o-Anisidine, 5-methyl-4-nitro-
• o-Anisidine, 5-methyl-4-nitro- (8CI)

Benzenamine, 2-methoxy-5-methyl-4-nitro-

CAS: 134-19-0

Formula: C₈H₁₀N₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 182.1766

Ref: IN-DA00HT4H

2-Methoxy-5-methyl-4-nitroaniline

CAS: 134-19-0

2-Methoxy-5-methyl-4-nitroaniline

Purity: 98%

Molecular weight: 182.18g/mol

Ref: 54-OR1062539

2-Methoxy-5-methyl-4-nitroaniline

CAS: 134-19-0

Formula: C₈H₁₀N₂O₃

Purity: 98%

Molecular weight: 182.179

Ref: 10-F547041

2-Methoxy-4-nitro-5-methylaniline

Controlled Product

CAS: 134-19-0

Applications 2-Methoxy-4-nitro-5-methylaniline is used as a reagent to synthesize 5- and 6-methoxybenzimidazole-1,3,5-triazines, compounds that act as inhibitors of phosphoinositide 3-kinase (PI3K) that have the potential to treat cancer.
References Miller, M., et al.: Bioorg. Med. Chem., 23, 802 (2013)

Formula: C₈H₁₀N₂O₃

Color and Shape: Neat

Molecular weight: 182.18

Ref: TR-M265370