CAS 134-35-0

5-Methyltetrahydrofolic acid

Description:

5-Methyltetrahydrofolic acid, also known as L-methylfolate, is a biologically active form of folate, which is a B-vitamin essential for various metabolic processes in the body. It plays a crucial role in the synthesis of nucleic acids and the metabolism of amino acids, particularly in the conversion of homocysteine to methionine. This compound is characterized by its molecular structure, which includes a pteridine ring, a para-aminobenzoic acid moiety, and a glutamic acid residue. It is water-soluble and typically exists as a pale yellow to orange crystalline powder. 5-Methyltetrahydrofolic acid is often used in dietary supplements and fortified foods, particularly for individuals with certain genetic polymorphisms that impair the metabolism of folate. Its bioavailability is higher than that of folic acid, making it an important compound in addressing folate deficiency and supporting overall health, particularly in pregnancy and during periods of rapid growth. Additionally, it is involved in the regulation of neurotransmitters, contributing to mental health and cognitive function.

Formula: C₂₀H₂₅N₇O₆

InChI: InChI=1S/C20H25N7O6/c1-27-12(9-23-16-15(27)18(31)26-20(21)25-16)8-22-11-4-2-10(3-5-11)17(30)24-13(19(32)33)6-7-14(28)29/h2-5,12-13,22H,6-9H2,1H3,(H,24,30)(H,28,29)(H,32,33)(H4,21,23,25,26,31)/t12?,13-/m0/s1

InChI key: InChIKey=ZNOVTXRBGFNYRX-ABLWVSNPSA-N

SMILES: CN1C2=C(NCC1CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)NC(N)=NC2=O

Synonyms:

• 2-[4-[(2-Amino-5-Methyl-4-Oxo-1,6,7,8-Tetrahydropteridin-6-Yl)Methylamino]Benzoyl]Aminopentanedioic Acid
• 5-Methyl-5,6,7,8-tetrahydrofolic acid
• 5-Methyl-5,6,7,8-tetrahydropteroyl-<span class="text-smallcaps">L</span>-glutamic acid
• 5-Methyltetrahydrofolate
• 5-Methyltetrahydrofolic acid
• 5-Methyltetrahydropteroyl monoglutamate
• 5-Methyltetrahydropteroylglutamic acid
• <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-
• <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[[(2-amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-
• Glutamic acid, N-[p-[[(2-amino-5,6,7,8-tetrahydro-4-hydroxy-5-methyl-6-pteridinyl)methyl]amino]benzoyl]-
• Glutamic acid, N-[p-[[(2-amino-5,6,7,8-tetrahydro-4-hydroxy-5-methyl-6-pteridinyl)methyl]amino]benzoyl]-, <span class="text-smallcaps">L</span>-
• Methyltetrahydrofolicacid
• N-(4-{[(2-amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}benzoyl)-D-glutamic acid
• N-Methyltetrahydrofolate
• N-Methyltetrahydrofolic acid
• N-[(4-{[(2-amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
• N-[4-({[(6S)-2-amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid
• N-[4-[[(2-Amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-<span class="text-smallcaps">L</span>-glutamic acid
• N⁵-Methyltetrahydrofolate
• N⁵-Methyltetrahydrofolic acid
• N⁵-Methyltetrahydropteroylglutamate
• Prefolic A
• n5-CH3-THF
• N-[4-[[(2-Amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
• L-Glutamic acid, N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-
• Glutamic acid, N-[p-[[(2-amino-5,6,7,8-tetrahydro-4-hydroxy-5-methyl-6-pteridinyl)methyl]amino]benzoyl]-, L-

5-Methyltetrahydrofolic acid

CAS: 134-35-0

5-Methyl THF is a bioactive, dominant dietary folate and main blood/CSF form.

Formula: C₂₀H₂₅N₇O₆

Purity: 99.47%

Color and Shape: Solid

Molecular weight: 459.46

Ref: TM-T13516

5-Methyltetrahydrofolic Acid Calcium Salt Trihydrate (Mixture of Diastereomers)

CAS: 134-35-0

Formula: C₂₀H₂₅N₇O₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 459.4558

Ref: IN-DA00800F

5-Methyltetrahydrofolic acid

CAS: 134-35-0

5-Methyltetrahydrofolic acid

Purity: ≥98%

Molecular weight: 459.46g/mol

Ref: 54-BUP14851

N-Methyltetrahydrofolic acid

CAS: 134-35-0

Formula: C₂₀H₂₅N₇O₆

Purity: ≥ 97.5% (anhydrous basis)

Color and Shape: White, off-white or yellow powder

Molecular weight: 459.46

Ref: 7W-GX7429

5-Methyl-Tetrahydrofolic Acid (Mixture of Diastereomers)

CAS: 134-35-0

Formula: C₂₀H₂₅N₇O₆

Molecular weight: 459.46

Ref: 4Z-F-2439

N-Methyltetrahydrofolic Acid

Controlled Product

CAS: 134-35-0

Applications N-Methyltetrahydrofolic acid (cas# 134-35-0) is a useful research chemical.

Formula: C₂₀H₂₅N₇O₆

Color and Shape: Neat

Molecular weight: 459.46

Ref: TR-M338145

5-Methyltetrahydrofolic Acid Calcium Salt Hydrate

Controlled Product

CAS: 134-35-0, 26560-38-3

Formula: C₂₀H₂₃CaN₇O₆•xH₂O

Color and Shape: White To Beige

Molecular weight: 497.52

Ref: TR-M330135

N-Methyltetrahydrofolic acid

CAS: 134-35-0

N-Methyltetrahydrofolic acid is a form of folic acid, which is an important vitamin for the production of red blood cells and the prevention of neural tube defects. It can be found in food such as leafy vegetables, whole grains, and citrus fruits. N-Methyltetrahydrofolic acid is important for DNA synthesis and energy metabolism. It also has been shown to exert antioxidant effects in human serum.

Formula: C₂₀H₂₅N₇O₆

Purity: Min. 97.5 Area-%

Color and Shape: White Powder

Molecular weight: 459.46 g/mol

Ref: 3D-FM16122

5-Methyltetrahydrofolic Acid

CAS: 134-35-0

Formula: C₂₀H₂₅N₇O₆

Purity: >95.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 459.46

Ref: 3B-M3575