CAS 134-63-4
:(-)-Lobeline Hydrochloride
Description:
(-)-Lobeline Hydrochloride is a chemical compound that is primarily known for its use in pharmacology and as a potential therapeutic agent. It is an alkaloid derived from the plant Lobelia inflata, commonly known as Indian tobacco. This compound exhibits a range of biological activities, including effects on the central nervous system, where it may act as a stimulant or a depressant depending on the dosage and context. (-)-Lobeline Hydrochloride is characterized by its chiral nature, with the "(-)" indicating its specific stereochemistry, which is crucial for its biological activity. The hydrochloride salt form enhances its solubility in water, making it more suitable for pharmaceutical applications. In addition to its potential therapeutic uses, (-)-Lobeline has been studied for its effects on nicotine addiction and as a respiratory stimulant. However, its use is subject to regulatory scrutiny due to safety and efficacy concerns. Overall, (-)-Lobeline Hydrochloride is a compound of interest in both medicinal chemistry and pharmacology, with ongoing research into its various applications.
Formula:C22H27NO2·ClH
InChI:InChI=1S/C22H27NO2.ClH/c1-23-19(15-21(24)17-9-4-2-5-10-17)13-8-14-20(23)16-22(25)18-11-6-3-7-12-18;/h2-7,9-12,19-21,24H,8,13-16H2,1H3;1H/t19-,20+,21-;/m0./s1
InChI key:InChIKey=MKMYPTLXLWOUSO-NFQNBQCWSA-N
SMILES:C([C@H](O)C1=CC=CC=C1)[C@H]2N(C)[C@@H](CC(=O)C3=CC=CC=C3)CCC2.Cl
Synonyms:- (-)-α-Lobeline hydrochloride
- 2-((2R,6S)-6-((S)-2-Hydroxy-2-Phenylethyl)-1-Methylpiperidin-2-Yl)-1-Phenylethanone Hydrochloride
- 2-(6-(2-Hydroxy-2-Phenethyl)-1-Methyl-2-Piperidyl)Acetophenone Hydrochloride
- 2-[6-(2-Hydroxy-2-Phenylethyl)-1-Methylpiperidin-2-Yl]-1-Phenylethanone Hydrochloride (1:1)
- 2-{(2R,6S)-6-[(2R)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl}-1-phenylethanone hydrochloride
- 2-{(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl}-1-phenylethanone
- 2-{(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl}-1-phenylethanone hydrochloride (1:1)
- Butane-1,4-Diyl Dimethanesulfonate
- Ethanone, 2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenyl-, hydrochloride
- Ethanone, 2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenyl-, hydrochloride (1:1)
- Ethanone, 2-[6-(2-hydroxy-2-phenylethyl)-1-methyl-2-piperidinyl]-1-phenyl-, hydrochloride, [2R-[2α,6α(S*)]]-
- Lobelin hydrochloride
- Lobeline HCL
- Lobron
- Vuf 10751
- Zoolobelin
- alpha-Lobeline hydrochloride
- (-)-Lobeline hydrochloride
- Lobeline hydrochloride
- Lobeline, hydrochloride
- ALPHA-LOBELIN HCL
- 2-(6-(beta-hydroxyphenethyl)-1-methyl-2-piperidyl)-acetophenonhydrochlor
- A-LOBELINE HCL
- 2-(6-[2-HYDROXY-2-PHENYLETHYL]-1-METHYL-2-PIPERIDINYL)-1-PHENYLETHANONE HYDROCHLORIDE
- 2-(6-[2-Hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl)-1-phenylethanone, L-Lobeline, Hydrochloride
- LOBELINE HCL, A-
- 2-[6-(.beta.-hydroxyphenethyl)-1-methyl-2-piperidyl]-,hydrochloride,(-)-Acetophenone
- 2-[(2r,6s)-6-[(2s)-2-hydroxy-2-phenyl-ethyl]-1-methyl-2-piperidyl]-1-phenyl-ethanone hydrochloride
- 2-[6-(2-HYDROXY-2-PHENETHYL)-1-METHYL-2-PIPERIDYL]ACETOPHENONE HCL
- Apolipoprotein B (LDL), Sheep anti-Human, Guinea pig, Swine (NO X w/Bovine, Horse, Dog, Cat, Rabbit, Chicken, Goat, Mouse, Rat)
- Lobelinhydrochloride
- L-LOBELINE HYDROCHLORIDE
- [2-[(2R,6S)-6-[(2S)-2-HYDROXYPHENETHYL]]-1-METHYL-2-PIPERIDYL]ACETOPHENONE HYDROCHLORIDE
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Found 11 products.
Lobeline hydrochloride
CAS:Formula:C22H28ClNO2Purity:98%Color and Shape:SolidMolecular weight:373.9162Lobeline hydrochloride
CAS:Lobeline hydrochloride (α-Lobeline hydrochloride) is a nicotinic receptor agonist, acting as an effective antagonist at both α4β2 and α3β2 neuronal nicotinicFormula:C22H27NO2·HClPurity:99.31% - 99.43%Color and Shape:Rosettes Of Slender Needles From Alc White To Off-White SolidMolecular weight:373.92Lobeline HCl
CAS:Formula:C22H27NO2·HClColor and Shape:White To Off-White SolidMolecular weight:337.46 36.46(-)-Lobeline hydrochloride
CAS:Formula:C22H27NO2·HClPurity:≥ 97.0%Color and Shape:White to off-white powderMolecular weight:373.92Lobeline Hydrochloride
CAS:Controlled ProductFormula:C22H27NO2·ClHColor and Shape:NeatMolecular weight:373.92a-Lobeline hydrochloride
CAS:<p>a-Lobeline hydrochloride is an alkaloid-based compound, which is primarily derived from the Lobelia plant species. It functions as a nicotinic acetylcholine receptor antagonist and dopamine transporter inhibitor, interacting with the central nervous system to modulate neurotransmitter activities. This compound has historically been explored for its potential in nicotine addiction treatment due to its ability to inhibit the reuptake of dopamine, thereby influencing reward pathways associated with addiction.</p>Formula:C22H28ClNO2Purity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:373.92 g/mol2-(6-(2-Hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethanone hydrochloride
CAS:Formula:C22H28ClNO2Purity:98%Molecular weight:373.92α-Lobeline Hydrochcloride
CAS:Controlled Product<p>Applications A neuronal nicotinic acetylcholine receptor agonist. A CNS stimulant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Damaj, M.I., et al.: J. Pharmacol. Exp. Ther., 282, 410 (1997), Toth, P.T., et al.: Eur. J. Pharmacol., 363, 75 (1998), Flammia, D., et al.: J. Med. Chem., 42, 3726 (1999), Dwoskin, P.A., et al.: Biochem. Pharmacol., 63, 89 (2002),<br></p>Formula:C22H27NO2·ClHColor and Shape:NeatMolecular weight:373.92
