CAS 134-63-4: (-)-Lobeline Hydrochloride
Description:(-)-Lobeline Hydrochloride is a chemical compound that is primarily known for its use in pharmacology and as a potential therapeutic agent. It is an alkaloid derived from the plant Lobelia inflata, commonly known as Indian tobacco. This compound exhibits a range of biological activities, including effects on the central nervous system, where it may act as a stimulant or a depressant depending on the dosage and context. (-)-Lobeline Hydrochloride is characterized by its chiral nature, with the "(-)" indicating its specific stereochemistry, which is crucial for its biological activity. The hydrochloride salt form enhances its solubility in water, making it more suitable for pharmaceutical applications. In addition to its potential therapeutic uses, (-)-Lobeline has been studied for its effects on nicotine addiction and as a respiratory stimulant. However, its use is subject to regulatory scrutiny due to safety and efficacy concerns. Overall, (-)-Lobeline Hydrochloride is a compound of interest in both medicinal chemistry and pharmacology, with ongoing research into its various applications.
Formula:C22H28ClNO2
InChI:InChI=1S/C22H27NO2.ClH/c1-23-19(15-21(24)17-9-4-2-5-10-17)13-8-14-20(23)16-22(25)18-11-6-3-7-12-18;/h2-7,9-12,19-21,24H,8,13-16H2,1H3;1H/t19-,20+,21-;/m0./s1
InChI key:InChIKey=MKMYPTLXLWOUSO-NFQNBQCWSA-N
SMILES:Cl.O=C(C=1C=CC=CC1)CC2N(C)C(CCC2)CC(O)C=3C=CC=CC3
- Synonyms:
- (-)-α-Lobeline hydrochloride
- 2-((2R,6S)-6-((S)-2-Hydroxy-2-Phenylethyl)-1-Methylpiperidin-2-Yl)-1-Phenylethanone Hydrochloride
- 2-(6-(2-Hydroxy-2-Phenethyl)-1-Methyl-2-Piperidyl)Acetophenone Hydrochloride
- 2-[6-(2-Hydroxy-2-Phenylethyl)-1-Methylpiperidin-2-Yl]-1-Phenylethanone Hydrochloride (1:1)
- 2-{(2R,6S)-6-[(2R)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl}-1-phenylethanone hydrochloride
- 2-{(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl}-1-phenylethanone
- 2-{(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl}-1-phenylethanone hydrochloride (1:1)
- Butane-1,4-Diyl Dimethanesulfonate
- Ethanone, 2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenyl-, hydrochloride
- Ethanone, 2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenyl-, hydrochloride (1:1)
- See more synonyms
- Ethanone, 2-[6-(2-hydroxy-2-phenylethyl)-1-methyl-2-piperidinyl]-1-phenyl-, hydrochloride, [2R-[2α,6α(S*)]]-
- Lobelin hydrochloride
- Lobeline HCL
- Lobron
- Vuf 10751
- Zoolobelin
- alpha-Lobeline hydrochloride
