CAS 134036-53-6

3-Amino-4-(1H-indol-5-ylmethylene)-2-pentenetricarbonitrile

Description:

3-Amino-4-(1H-indol-5-ylmethylene)-2-pentenetricarbonitrile, with the CAS number 134036-53-6, is a chemical compound characterized by its complex structure, which includes an indole moiety and multiple cyano groups. This compound typically exhibits properties associated with both amines and nitriles, such as potential basicity due to the amino group and reactivity due to the presence of cyano groups. It may display significant biological activity, making it of interest in medicinal chemistry and drug development. The indole structure often contributes to aromaticity and can participate in various chemical reactions, including electrophilic substitutions. Additionally, the presence of multiple cyano groups suggests potential applications in materials science, particularly in the synthesis of polymers or as precursors for other chemical transformations. The compound's solubility, stability, and reactivity can vary depending on the solvent and environmental conditions, which are important factors to consider in practical applications. Overall, this compound represents a unique intersection of organic chemistry and potential pharmacological applications.

Formula: C₁₅H₉N₅

InChI: InChI=1S/C15H9N5/c16-7-12(15(19)13(8-17)9-18)6-10-1-2-14-11(5-10)3-4-20-14/h1-6,20H,19H2

InChI key: InChIKey=CMMDWEJTQUTCKG-UHFFFAOYSA-N

SMILES: C(=C(C(=C(C#N)C#N)N)C#N)C=1C=C2C(=CC1)NC=C2

Synonyms:

• NSC 651712
• AG 370
• 2-Pentenetricarbonitrile, 3-amino-4-(1H-indol-5-ylmethylene)-
• 1,3-Butadiene-1,1,3-tricarbonitrile, 2-amino-4-(1H-indol-5-yl)-
• 3-Amino-4-(1H-indol-5-ylmethylene)-2-pentenetricarbonitrile

AG-370

CAS: 134036-53-6

AG 370, an indole tyrphostin, functions as a powerful inhibitor of PDGF-induced mitogenesis, demonstrating an IC50 of 20 μM.

Formula: C₁₅H₉N₅

Color and Shape: Solid

Molecular weight: 259.27

Ref: TM-T21784