CAS 13406-51-4

N6-Methyl-2-methylthioadenosine

Description:

N6-Methyl-2-methylthioadenosine (MTA) is a naturally occurring compound that plays a significant role in cellular metabolism and signaling. It is a derivative of adenosine, featuring a methyl group at the N6 position and a methylthio group at the 2 position of the adenine ring. MTA is involved in the methionine salvage pathway, which recycles methionine from S-adenosylhomocysteine, and is important in various biological processes, including cellular proliferation and differentiation. The compound exhibits a range of biological activities, including potential anti-inflammatory and anti-cancer properties. MTA is soluble in water and polar organic solvents, making it accessible for various biochemical applications. Its structure allows it to interact with various enzymes and receptors, influencing metabolic pathways. Additionally, MTA's role as a signaling molecule in the regulation of cellular functions highlights its importance in both normal physiology and disease states. Overall, N6-Methyl-2-methylthioadenosine is a significant compound in biochemistry with implications in health and disease.

Formula: C₁₂H₁₇N₅O₄S

Synonyms:

• 2-Methylthio-N6-methyladenosine
• N6-Methyl-2-methyl thioadenosine,RNA-modified nucleoside ms2m6A
• N6-Methyl-2-methylthioadenosine
• Adenosine, N-methyl-2-(methylthio)-

N6-Methyl-2-methylthioadenosine

CAS: 13406-51-4

N6-Methyl-2-methylthioadenosine is a thiomethylated protected nucleotide that can be used in the synthesis of nucleoside derivatives.

Formula: C₁₂H₁₇N₅O₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 327.36

Ref: TM-TNU0160

2-Methylthio-N6-methyladenosine

CAS: 13406-51-4

2-Methylthio-N6-methyladenosine is an adenosine nucleoside that is found in the DNA of eukaryotes. It is similar to 2-methylthio-n6-isopentenyladenosine, which is a modified form of n6-methyladenosine. The chemical structures of both molecules are related to the thermodynamic properties of the molecule and their ability to be postsynthetically modified. These modifications can lead to changes in their translation, which can have implications for the development and progression of disease. 2-Methylthio-N6-methyladenosine has a role in epigenetics, which is defined as changes in gene expression without any alterations in DNA sequence. In this case, it may modify the chloride ion concentration by changing its chemical structure, leading to epigenetic changes that can affect how genes are expressed or translated into proteins.

Formula: C₁₂H₁₇N₅O₄S

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 327.36 g/mol

Ref: 3D-NM159489