CAS 134069-68-4

8-[4,4-bis(4-fluorophenyl)butyl]-3-tert-butyl-4-methylidene-1-oxa-3,8-diazaspiro[4.5]decan-2-one

Description:

The chemical substance known as "8-[4,4-bis(4-fluorophenyl)butyl]-3-tert-butyl-4-methylidene-1-oxa-3,8-diazaspiro[4.5]decan-2-one," with the CAS number 134069-68-4, is a complex organic compound characterized by its unique spirocyclic structure, which incorporates both nitrogen and oxygen heteroatoms. This compound features a tert-butyl group and a fluorinated phenyl moiety, contributing to its potential lipophilicity and biological activity. The presence of the oxa and diaza functionalities suggests that it may exhibit interesting chemical reactivity and could be of interest in medicinal chemistry or material science. Its spiro structure may impart distinctive conformational properties, influencing its interactions with biological targets or its behavior in various chemical environments. Additionally, the fluorine substituents can enhance the compound's stability and alter its electronic properties, making it a candidate for further investigation in drug development or as a synthetic intermediate. Overall, this compound's intricate structure and functional groups suggest a range of potential applications in various fields of chemistry.

Formula: C₂₈H₃₄F₂N₂O₂

InChI: InChI=1/C28H34F2N2O2/c1-20-28(34-26(33)32(20)27(2,3)4)15-18-31(19-16-28)17-5-6-25(21-7-11-23(29)12-8-21)22-9-13-24(30)14-10-22/h7-14,25H,1,5-6,15-19H2,2-4H3

SMILES: C=C1C2(CCN(CCCC(c3ccc(cc3)F)c3ccc(cc3)F)CC2)OC(=O)N1C(C)(C)C

Synonyms:

• 1-Oxa-3,8-diazaspiro(4.5)decan-2-one, 8-(4,4-bis(4-fluorophenyl)butyl)-3-(1,1-dimethylethyl)-4-methylene-

TDN 345

CAS: 134069-68-4

TDN 345 is a catecholaminergic, blocker. It blocks the signal transduction pathway by inhibiting the neurotransmitter receptor and blocking the binding of neurotransmitters to their receptors. TDN 345 is administered orally, at doses ranging from 3 mg to 10 mg per day, to control levels of catecholamines in patients with carotid artery disease and cerebral vascular disease. TDN 345 has been shown to reduce the growth factor-mediated, cerebrovascular diseases. TDN 345 may also be useful in treating glioma and etidocaine-induced pain.

Formula: C₂₈H₃₄F₂N₂O₂

Purity: Min. 95%

Molecular weight: 468.6 g/mol

Ref: 3D-JFA06968

TDN345

CAS: 134069-68-4

TDN345 is a antagonist of Ca2+, for the treatment of vascular and senile dementia including Alzheimer's disease.

Formula: C₂₈H₃₄F₂N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 468.58

Ref: TM-T13107