CAS 13410-30-5

2-(2-Deoxy-β-D-erythro-pentofuranosyl)-6-methyl-1,2,4-triazine-3,5(2H,4H)-dione

Description:

2-(2-Deoxy-β-D-erythro-pentofuranosyl)-6-methyl-1,2,4-triazine-3,5(2H,4H)-dione, with the CAS number 13410-30-5, is a chemical compound that belongs to the class of triazine derivatives. This substance features a triazine ring, which is a six-membered heterocyclic compound containing three nitrogen atoms. The presence of the 2-deoxy-β-D-erythro-pentofuranosyl moiety indicates that it is a nucleoside analog, which may have implications in biological activity, particularly in relation to nucleic acid metabolism. The methyl group at the 6-position of the triazine ring can influence its chemical reactivity and biological interactions. This compound is of interest in medicinal chemistry and may exhibit properties relevant to antiviral or anticancer activities. Its structural characteristics suggest potential for hydrogen bonding and interactions with biological macromolecules, making it a candidate for further research in pharmacology and biochemistry. However, specific applications and biological effects would require detailed experimental studies to elucidate its mechanisms of action.

Formula: C₉H₁₃N₃O₅

InChI: InChI=1S/C9H13N3O5/c1-4-8(15)10-9(16)12(11-4)7-2-5(14)6(3-13)17-7/h5-7,13-14H,2-3H2,1H3,(H,10,15,16)/t5-,6+,7+/m0/s1

InChI key: InChIKey=LXHOFEUVCQUXRZ-RRKCRQDMSA-N

SMILES: O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)N=C(C)C(=O)N1

Synonyms:

• NSC 80211
• 6-Azathymidine
• as-Triazine-3,5(2H,4H)-dione, 2-(2-deoxy-β-D-erythro-pentofuranosyl)-6-methyl-
• 2-(2-Deoxy-β-D-erythro-pentofuranosyl)-6-methyl-1,2,4-triazine-3,5(2H,4H)-dione
• 1,2,4-Triazine-3,5(2H,4H)-dione, 2-(2-deoxy-β-D-erythro-pentofuranosyl)-6-methyl-

6-Azathymidine

CAS: 13410-30-5

6-Azathymidine is an antiviral agent that prevents the synthesis of viral DNA. It is a nucleoside analogue that contains a hydroxyl group at the 6 position on a pyrimidine ring. This compound has been shown to be effective in treating HIV infection and cancer, as well as herpes simplex virus and influenza virus. 6-Azathymidine inhibits the enzyme ribonucleotide reductase, which is responsible for converting ribonucleotides into deoxyribonucleotides, thereby blocking DNA synthesis. The phosphate derivatives of this drug have been shown to inhibit the biosynthesis of human immunodeficiency virus (HIV) by interfering with intermolecular hydrogen bonding between guanine and adenine.

Formula: C₉H₁₃N₃O₅

Purity: Min. 95%

Molecular weight: 243.22 g/mol

Ref: 3D-NAA41030