Trimethylsilyl acetate (TMS acetate) is an organosilicon compound characterized by the presence of a trimethylsilyl group attached to an acetate moiety. It is typically a colorless, volatile liquid with a mild, sweet odor. This compound is known for its utility as a derivatizing agent in gas chromatography and mass spectrometry, particularly for the analysis of alcohols and carboxylic acids, as it enhances volatility and stability of the analytes. TMS acetate is soluble in organic solvents such as ether and dichloromethane, but it is less soluble in water due to its hydrophobic silyl group. It is relatively stable under normal conditions but should be handled with care, as it can react with moisture, leading to the release of acetic acid and the formation of silanol compounds. Additionally, it is important to consider safety precautions when working with this substance, as it may pose health risks if inhaled or ingested. Overall, trimethylsilyl acetate is a valuable reagent in organic synthesis and analytical chemistry.

Trimethylsilyl Acetate

13411-48-8: Trimethylsilyl acetate (TMS acetate) is an organosilicon compound characterized by the presence of a trimethylsilyl group attached to an acetate moiety. It is typically a colorless, volatile liquid with a mild, sweet odor. This compound is known for its utility as a derivatizing agent in gas chromatography and mass spectrometry, particularly for the analysis of alcohols and carboxylic acids, as it enhances volatility and stability of the analytes. TMS acetate is soluble in organic solvents such as ether and dichloromethane, but it is less soluble in water due to its hydrophobic silyl group. It is relatively stable under normal conditions but should be handled with care, as it can react with moisture, leading to the release of acetic acid and the formation of silanol compounds. Additionally, it is important to consider safety precautions when working with this substance, as it may pose health risks if inhaled or ingested. Overall, trimethylsilyl acetate is a valuable reagent in organic synthesis and analytical chemistry.

CAS 13411-48-8

Trimethylsilyl Acetate

Acetyltrimethylsilane

Ref: 10-S25017