CAS 1341224-83-6

PF-4136309

Description:

PF-4136309, identified by its CAS number 1341224-83-6, is a small molecule that has been investigated primarily for its potential therapeutic applications, particularly in the context of cancer treatment. It functions as a selective inhibitor of certain kinases, which are enzymes that play crucial roles in various cellular processes, including cell growth and division. The compound's mechanism of action typically involves the modulation of signaling pathways that are often dysregulated in cancer cells. In terms of its physical and chemical properties, PF-4136309 is characterized by its specific molecular structure, which includes functional groups that contribute to its biological activity and solubility. The compound's efficacy and safety profile are evaluated through preclinical and clinical studies, focusing on its ability to inhibit tumor growth and its potential side effects. As with many investigational drugs, ongoing research aims to better understand its pharmacokinetics, pharmacodynamics, and overall therapeutic potential in oncology.

Synonyms:

• Benzamide, N-[2-[(3S)-3-[[trans-4-hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl]amino]-1-pyrrolidinyl]-2-oxoethyl]-3-(trifluoromethyl)-
• N-(2-((S)-3-(((1r,4S)-4-hydroxy-4-(5-(pyrimidin-2-yl) yridine-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide

N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide

CAS: 1341224-83-6

Formula: C₂₉H₃₁F₃N₆O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 568.5900

Ref: IN-DA00392L

PF-4136309

CAS: 1341224-83-6

PF-4136309

Purity: ≥98%

Molecular weight: 568.59g/mol

Ref: 54-BUP15176

PF-4136309

CAS: 1341224-83-6

PF-4136309

Purity: 98%

Molecular weight: 568.59g/mol

Ref: 54-BISN0025

PF-4136309

CAS: 1341224-83-6

PF-4136309 (INCB8761) is a specific, effective, and orally bioavailable CCR2 antagonist.

Formula: C₂₉H₃₁F₃N₆O₃

Purity: 98.85% - 99.47%

Color and Shape: Solid

Molecular weight: 568.59

Ref: TM-T3430

INCB 8761

CAS: 1341224-83-6

Chemokine receptor 2 antagonist

Formula: C₂₉H₃₁F₃N₆O₃

Purity: Min. 95%

Molecular weight: 568.59 g/mol

Ref: 3D-FI104116