CAS 134217-15-5

9H-Purin-6-amine, 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-2-fluoro-

Description:

9H-Purin-6-amine, 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-2-fluoro-, commonly known as a nucleoside analog, is characterized by its structural features that include a purine base and a sugar moiety modified with fluorine atoms. This compound is notable for its potential antiviral properties, particularly against certain viral infections, as it can interfere with viral replication processes. The presence of fluorine atoms enhances its stability and bioactivity compared to its non-fluorinated counterparts. The compound typically exhibits solubility in polar solvents, which is a common trait among nucleosides. Its mechanism of action often involves incorporation into viral RNA or DNA, leading to termination of nucleic acid synthesis. Additionally, the compound may exhibit varying degrees of cytotoxicity, which is an important consideration in therapeutic applications. Overall, this substance represents a significant area of interest in medicinal chemistry and pharmacology, particularly in the development of antiviral therapies.

Formula: C₁₀H₁₁F₂N₅O₃

2-Fluoro-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine

CAS: 134217-15-5

2-Fluoro-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine is an antiviral drug that inhibits the synthesis of viral DNA and RNA. It is a synthetic nucleoside analogue with antiviral activity against herpes simplex virus type 1, herpes simplex virus type 2, varicella zoster virus, cytomegalovirus, Epstein Barr virus, and human immunodeficiency virus type 1. This compound is also used as a building block in the preparation of phosphoramidites for chemical synthesis of deoxyribonucleosides. 2-Fluoro-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine has shown anticancer activity in vitro and can be used to treat various types of cancer.

Formula: C₁₀H₁₁F₂N₅O₃

Purity: Min. 95%

Molecular weight: 287.22 g/mol

Ref: 3D-NF11536