CAS 13422-51-0

Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3'-ester with (5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole-κN3)

Description:

Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3'-ester with (5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole-κN3) is a complex chemical compound that features a cobalt-containing structure, which is significant in biological systems, particularly in vitamin B12 metabolism. This compound is characterized by its coordination with cobalt, which plays a crucial role in various enzymatic reactions. The presence of a phosphate group suggests potential solubility in aqueous environments, enhancing its bioavailability. The 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole moiety indicates a structural similarity to nucleosides, which may influence its interaction with biological macromolecules. As an inner salt, it likely exhibits unique ionic properties that can affect its stability and reactivity. Overall, this compound's intricate structure and functional groups suggest potential applications in biochemistry and pharmacology, particularly in studies related to vitamin B12 derivatives and their physiological roles. Further research would be necessary to elucidate its specific biological activities and potential therapeutic uses.

Formula: C₆₂H₉₀ClCoN₁₃O₁₅P

InChI: InChI=1S/C62H90N13O14P.Co.H2O/c1-29-20-40-41(21-30(29)2)75(28-70-40)56-52(84)53(42(27-76)87-56)89-90(85,86)88-31(3)26-69-49(83)19-15-36-50-32(4)54-58(6,7)34(12-16-43(63)77)38(71-54)22-39-35(13-17-44(64)78)59(8,23-46(66)80)55(72-39)33(5)51-37(14-18-45(65)79)61(10,25-48(68)82)62(11,74-51)57(73-50)60(36,9)24-47(67)81;;/h20-22,28,31,34-37,42,52-53,56-57,76,84H,12-19,23-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;1H2/q;+3;/p-3

InChI key: InChIKey=YOZNUFWCRFCGIH-UHFFFAOYSA-K

SMILES: [OH-][Co+3]1234[N]=5C6(C)C7[N-]1C(C(C)(C7CC(N)=O)CCC(=O)NCC(C)OP(=O)([O-])OC8C(O)C(N9C=[N]2C=%10C9=CC(C)=C(C)C%10)OC8CO)=C(C)C%11=[N]3C(=CC%12=[N]4C(=C(C)C5C(CCC(N)=O)C6(CC(N)=O)C)C(CC(N)=O)(C)C%12CCC(N)=O)C(C)(C)C%11CCC(N)=O

Synonyms:

• Alpha Cobione
• AlphaRedisol
• Axlon
• Ciplamin H
• Cobalamin, hydroxo-
• Cobalex
• Cobalin H
• Cobinamide hydroxide phosphate 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole inner salt
• Cobinamide hydroxide phosphate 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosylbenzimidazole inner salt
• Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3′-ester with (5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole-κN³)
• Cobinamide, dihydroxide, dihydrogen phosphate (ester), mono (inner salt), 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole
• Cobinamide, dihydroxide, dihydrogen phosphate (ester), mono(inner salt), 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole
• Cobinamide, dihydroxide, dihydrogen phosphate (ester), mono(inner salt), 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole
• Cobinamide, dihydroxide, dihydrogen phosphate (ester), mono(inner salt), 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosylbenzimidazole
• Codroxomin
• Cyanokit
• Depovit B12
• Docclan
• Docelan
• Docevita
• Droxomin
• Ducobee Hy
• Duradoce
• Duralta-12
• Hidroxocobalamina
• Hydrocobalamin
• Hydrogrisevit
• Hydrovit
• Hydroxocobalamin
• Hydroxocobalamine
• Hydroxocobemine
• Hydroxy vitamin B12
• Hydroxy vitamin B₁₂
• Hydroxycobalamin
• Hydroxycobalamine
• Hyxobamine
• Idrogrisevit
• Megamilbedoce
• Neo-Betalin 12
• Neo-Cytamen
• Neo-Macrabin
• Neo-Rojamin
• OH-Duphar
• Oxobemin
• Primabalt RP
• Redisol H
• Sytobex H
• Vibeden
• Vitadurin
• Vitamin B12a
• Vitamin B_12a
• α-(5,6-Dimethylbenzimidazolyl)hydroxocobamide
• Cobinamide,Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3'-ester with(5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole-kN3)
• Hydroxocobalamin Vitamin B12
• hydroxy-[(1R,2R,3R,4Z,7S,9Z,12S,13S,14Z,17S,18S,19R)-2,13,18-tris(2-amino-2-oxo-ethyl)-7,12,17-tris(3-amino-3-oxo-propyl)-3-[3-[[(2R)-2-[[(2R,3S,4R,5S)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl]oxy-oxido-phosphoryl]oxypropyl]amino]-3-oxo-propyl]-3,5,8,8,13,15,18,19-octamethyl-2,7,12,17-tetrahydro-1H-corrin-21-yl]cobalt(1+) hydrochloride
• Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3′-ester with (5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole-κN3)
• Cobinamide,dihydroxide, dihydrogen phosphate (ester), mono(inner salt), 3'-ester with5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole
• alphacobione
• HYDROXOCOBALAMINE HYDROCHLORIDE
• Hydroxocobalamin CRS
• Hydroxocobalamin Acetate/Hydroxocobalamin HCL (Vitamin B12)
• hydroxycobalamin (both acetate and HCl)
• Coalpha-[alpha-(5,6-dimethylbenzimidazolyl)]-Cobeta-hydroxocobamide
• cobinamide,dihydroxide,dihydrogenphosphate(ester),mono(innersalt),3’-est
• vitaminb(sub12a)
• sterwith5,6-dimethyl-1-alpha-d-ribofuranosylbenzimidazole
• erwith5,6-dimethyl-1-alpha-d-ribofuranosyl-1h-benzimidazole
• HYDOXOCOBALAMIN
• Hydroxocobalamin/Hydrovit/vitamin B12 CAS NO.13422-51-0
• axion
• hydroxo-cobalami
• HYDROXYCOBALAMIN HYDROCHLORIDE
• High purity Hydroxocobalamin
• lyovit-h
• OH-CBL HCL
• ohb12
• cobinamidehydroxidephosphate3’-esterwith5,6-dimethyl-1-alpha-d-ribofuranos
• Cyanocobalamin Impurity 13
• oxolamine(arcum)
• ALPHA-(5,6-DIMETHYLBENZIMIDAZOLYL)HYDROXOCOBAMIDE HYDROCHLORIDE
• VITAMIN B12A HYDROCHLORIDE
• depogamma
• docelvita
• Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3-ester with (5,6-dimethyl-1-.alpha.-D-ribofuranosyl-1H-benzimidazole-.kappa.N3)
• ciplaminh
• HYDROXOCOBALAMIN,USP
• alpha-(5,6-dimethylbenzimidazolyl)hydroxocobamide
• hydroxyvitaminb12
• primabaltrp
• HYDROXOCOBALAMIN HYDROCHLORIDE
• VITAMIN B12B
• Hydroxocobalamin (~90%)
• cobinamide,dihydroxide,dihydrogenphosphate(ester),mono(innersalt),3’-e
• hydrobamine
• Hydroxocobalam
• HydroxocobalaMin (VitaMin B12a)
• redisolh
• AQUOCOBALAMIN CHLORIDE
• Hydroxocobalamin/VitaminB12Cp2000

Hydroxocobalamin

CAS: 13422-51-0

Hydroxocobalamin (Vitamin B12a) is a cyanide antidote and essential nutrient. Used for cyanide poisoning, Cbl-C defects, and Vitamin B12 deficiency research.

Formula: C₆₂H₈₉CoN₁₃O₁₅P

Purity: 99.81%

Color and Shape: Purple Solid

Molecular weight: 1346.36

Ref: TM-T78476

Hydroxocobalamin

CAS: 13422-51-0

Hydroxocobalamin

Purity: 97%

Molecular weight: 1346.36g/mol

Ref: 54-IN12362

Vitamin B12a (Hydroxocobalamin)

CAS: 13422-51-0

Formula: C₆₂H₈₉CoN₁₃O₁₅P

Molecular weight: 1346.38

Ref: 4Z-V-035027

Hydroxocobalamin

CAS: 13422-51-0

Formula: C₆₂H₈₉CoN₁₃O₁₅P

Molecular weight: 1346.38

Ref: ST-EA-CP-H13000

Hydroxocobalamin (>90%)

CAS: 13422-51-0

Stability Hygroscopic
Applications Hydroxocobalamin is an intermediate in the synthesis of Nitritocobalamin(N490240) is a useful synthetic intermediate in the synthesis of Hydroxocobalamin Acetate (H826800); a physiological analog of vitamin B12 where the CN group is replaced with OH. Exists in aqueous solution as an equilibrium mixture of the hydroxy isomer and the ionic aqua isomer (aquacobalamin). Precursor of the coenzymes methylcobalamin and cobamamide. Coordination Compound. Vitamin (hematopoietic).
References Kaczka, E.A., et al.: Science, 112, 354 (1950); Friedrich, W., et al.: Vitamins, 837 (1988); Forsyth, J.C., et al.: Clin. Toxicol., 31, 277 (1993)

Formula: C₆₂H₈₉CoN₁₃O₁₅P

Purity: >90%

Color and Shape: Neat

Molecular weight: 1346.36

Ref: TR-H862820

Hydroxocobalamin

CAS: 13422-51-0

Purity: 97%

Ref: 10-F551624

Hydroxocobalamin

CAS: 13422-51-0

Hydroxocobalamin is a vitamin that has a specific antidote for cyanide poisoning. Hydroxocobalamin is synthesized from hydroxycobalamin, which is produced by the reaction of cyanide with cytochrome c in the presence of ferric ion, and it can be administered orally or intravenously. Hydroxocobalamin reacts with cyanide to form cyanocobalamin and releases the toxic hydrogen cyanide gas as a by-product. Hydroxocobalamin also has effects on cardiac tissue as it increases mitochondrial cytochrome C oxidase activity. The thermodynamic data for hydroxocobalamin are not available because this compound is unstable in water.

Formula: C₆₂H₈₉CoN₁₃O₁₅P

Purity: 90%Min

Color and Shape: Powder

Molecular weight: 1,346.35 g/mol

Ref: 3D-FH61514

Cyanocobalamin EP Impurity H

CAS: 13422-51-0

Formula: C₆₂H₈₉CoN₁₃O₁₅P

Molecular weight: 1346.4

Ref: ST-EA-CP-C132017

Methylcobalamin Impurity 11

CAS: 13422-51-0

Formula: C₆₂H₈₉CoN₁₃O₁₅P

Molecular weight: 1346.38

Ref: 4Z-V-035017