CAS 13422-55-4

Methylcobalamin

Description:

Methylcobalamin, with the CAS number 13422-55-4, is a biologically active form of vitamin B12, also known as cobalamin. It is a water-soluble vitamin that plays a crucial role in various physiological processes, including DNA synthesis, red blood cell formation, and neurological function. Methylcobalamin is characterized by its cobalt-containing corrin ring structure, which is essential for its biological activity. It is often used as a dietary supplement and is particularly important for individuals with vitamin B12 deficiency, which can lead to anemia and neurological issues. Methylcobalamin is known for its ability to cross the blood-brain barrier, making it beneficial for neurological health. In terms of stability, it is sensitive to light and heat, which can affect its potency. The substance is typically administered via oral supplements or injections, depending on the individual's needs. Overall, methylcobalamin is vital for maintaining healthy nerve function and metabolic processes in the body.

Formula: C₆₃H₉₁CoN₁₃O₁₄P

InChI: InChI=1S/C62H90N13O14P.CH3.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);1H3;/q;-1;+3/p-2/t31-,34-,35-,36-,37+,41-,52?,53-,56+,57+,59-,60+,61+,62+;;/m1../s1

InChI key: InChIKey=ZFLASALABLFSNM-FGIXMQGJSA-L

SMILES: [CH3-][Co+3]1234[N]=5[C@@]6(C)[C@]7([N-]1C([C@@](C)([C@H]7CC(N)=O)CCC(=O)NC[C@@H](C)OP(=O)([O-])O[C@H]8C(O)([C@@H](N9C=[N]2C=%10C9=CC(C)=C(C)C%10)O[C@@H]8CO)[H])=C(C)C%11=[N]3C(=CC%12=[N]4C(=C(C)C5[C@@H](CCC(N)=O)[C@@]6(CC(N)=O)C)[C@](CC(N)=O)(C)[C@@H]%12CCC(N)=O)C(C)(C)[C@@H]%11CCC(N)=O)[H]

Synonyms:

• Algobaz
• Co-Methylcobalamin
• Cobalamin, Co-methyl-
• Cobinamide, Co-methyl deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole
• Cobinamide, Co-methyl deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole
• Cobinamide, Co-methyl deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole
• Cobinamide, Co-methyl deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosylbenzimidazole
• Cobinamide, Co-methyl derivative, hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole
• Cobinamide, Co-methyl-, dihydrogen phosphate (ester), inner salt, 3′-ester with (5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole-κN³)
• Hitocobamin M
• MeCbl
• Mecobalamin
• Mecobalamina
• Mecobalamine
• Methycobal
• Methyl cobalamine
• Methyl vitamin B12
• Methyl vitamin B₁₂
• Methyl-5,6-dimethylbenzimidazolylcobalamin
• Methyl-B12
• Methyl-B₁₂
• Methylcob(III)alamin
• Methylcobalamin
• Methylcobaz

Methylcobalamin Hydrate

CAS: 13422-55-4, 288315-09-3

Formula: C₆₃H₉₁CoN₁₃O₁₄P·xH₂O

Purity: >98.0%(N)

Color and Shape: Red to Dark red to Brown powder to crystal

Molecular weight: 1,344.40 (as Anhydrous)

Ref: 3B-M2742

Methylcobalamin

CAS: 13422-55-4

Vitamin b12 (cyanocobalamin and related compounds with vitamin b12 activity) and its derivatives

Formula: C₆₃H₉₁CoN₁₃O₁₄P

Color and Shape: Dark Red Powder

Molecular weight: 1343.5878

Ref: 45-1424550

Methylcobalamin

CAS: 13422-55-4

Formula: C₆₃H₉₁CoN₁₃O₁₄P

Purity: 98%

Color and Shape: Solid

Molecular weight: 1344.3823

Ref: IN-DA003S3I

Methylcobalamin-d3

CAS: 13422-55-4

Formula: C₆₃H₈₈D₃CoN₁₃O₁₄P

Molecular weight: 1347.42

Ref: 4Z-V-035018

Methylcobalamin hydrate

CAS: 13422-55-4

Formula: C₆₃H₉₁CoN₁₃O₁₄P·xH₂O

Purity: 98.0 - 102.0 % (dried basis)

Color and Shape: Dark red crystalline powder or crystals

Molecular weight: 1344.41 (anhydrous)

Ref: 7W-GV9033

Methylcobalamin

CAS: 13422-55-4

Formula: C₆₃H₉₁CoN₁₃O₁₄P

Color and Shape: Neat

Molecular weight: 1344.38

Ref: 04-C15084870

Methylcobalamin

CAS: 13422-55-4

Methylcobalamin, a B12 form, aids homocysteine metabolism; treats nutritional issues, Alzheimer's, and rheumatoid arthritis.

Formula: C₆₃H₉₁CoN₁₃O₁₄P

Purity: 98% - 98.23%

Color and Shape: Solid

Molecular weight: 1344.38

Ref: TM-T3136

Methylcobalamin-13C-d3

CAS: 13422-55-4

Formula: CC₆₂H₈₈D₃CoN₁₃O₁₄P

Molecular weight: 1348.42

Ref: 4Z-V-035006

Mecobalamin RS

CAS: 13422-55-4

Color and Shape: Dark Red

Ref: 2K-1159000021

Mecobalamin-d3

Controlled Product

CAS: 13422-55-4

Stability Light Sensitive
Applications Isotope labelled Mecobalamin (M202800), one of the biologically active forms of vitamin B12; differing only by the substitution of a methyl for the cyano group. Coenzyme required in the biosynthesis of methionine. Vitamin (hematopoietic).
References Kisliuk, R.L., Biochem. J., 75, 467 (1960), Guest, J.R., et al.: Nature, 195, 340 (1962), Dolphin, D., et al.: Methods Enzymol., 18, 34 (1971), Beck, W.S., et al.: Am. J. Hematol., 34, 83 (1990),

Formula: C₆₃H₈₈D₃CoN₁₃O₁₄P

Color and Shape: Dark Red

Molecular weight: 1347.4

Ref: TR-M202802

Mecobalamin

CAS: 13422-55-4

Stability Light Sensitie
Applications One of the biologically active forms of vitamin B12; differing only by the substitution of a methyl for the cyano group. Coenzyme required in the biosynthesis of methionine. Vitamin (hematopoietic).
References Kisliuk, R.L., Biochem. J., 75, 467 (1960), Guest, J.R., et al.: Nature, 195, 340 (1962), Dolphin, D., et al.: Methods Enzymol., 18, 34 (1971), Beck, W.S., et al.: Am. J. Hematol., 34, 83 (1990),

Formula: C₆₃H₉₁CoN₁₃O₁₄P

Color and Shape: Neat

Molecular weight: 1344.38

Ref: TR-M202800

Mecobalamin

CAS: 13422-55-4

Mecobalamin is a form of vitamin B12 that is used to treat bowel disease. It binds to the target enzymes methionine synthase and cystathionine beta-synthase, which are involved in the synthesis of methionine and cysteine respectively. Mecobalamin has been shown to be effective in treating Crohn's disease when given as a low-dose therapy. Mecobalamin also has demonstrated therapeutic effects in ulcerative colitis, but had no effect on patients with non-ulcerative colitis. Mecobalamin was well tolerated at the doses tested and did not produce any significant changes in blood cell counts or liver enzyme activities.
Mecobalamin is not absorbed orally, so it is given by injection or intravenously. The drug can be injected subcutaneously, intramuscularly, or intravenously.

Formula: C₆₃H₉₁CoN₁₃O₁₄P

Purity: Min. 95%

Color and Shape: Red Powder

Molecular weight: 1,344.38 g/mol

Ref: 3D-FM25030

Vitamin B12a (B12 Analog) ExiPlus, Multi-Compendial, 98%-102%

CAS: 13422-55-4

Formula: C₆₃H₉₁CoN₁₃O₁₄P

Purity: 98 - 102%

Color and Shape: Dark red, Crystalline powder, Clear, Red

Molecular weight: 1355.38

Ref: SR-79446

Mecobalamin-13CD3

Controlled Product

CAS: 13422-55-4

Formula: C₆₂CH₈₈D₃CoN₁₃O₁₄P

Color and Shape: Neat

Molecular weight: 1348.42

Ref: TR-M202801