CAS 1343040-07-2

2-{cyclopentyl[(9H-fluoren-9-ylmethoxy)carbonyl]amino}acetic acid

CAS: 1343040-07-2

Formula: C₂₂H₂₃NO₄

Purity: 98%

Molecular weight: 365.4223

Ref: IN-DA01AJM8

N-(((9h-Fluoren-9-yl)methoxy)carbonyl)-N-cyclopentylglycine

CAS: 1343040-07-2

N-(((9h-Fluoren-9-yl)methoxy)carbonyl)-N-cyclopentylglycine

Purity: 98%

Molecular weight: 365.42g/mol

Ref: 54-OR77964

N-(((9h-Fluoren-9-yl)methoxy)carbonyl)-N-cyclopentylglycine

CAS: 1343040-07-2

Purity: 98%

Molecular weight: 365.4289856

Ref: 10-F634020

2-{Cyclopentyl[(9H-fluoren-9-ylmethoxy)carbonyl]amino}acetic acid

CAS: 1343040-07-2

The synthesis of 2-{Cyclopentyl[(9H-fluoren-9-ylmethoxy)carbonyl]amino}acetic acid is accomplished through an asymmetric, stereoselective, catalytic route. The first step in the synthesis is conversion of glycine to the corresponding N-protected glycine methyl ester by reaction with benzyl chloroformate followed by protection of both carboxylic acid groups as FMOC derivatives. The key steps are a diastereoselective hydrogenation of the cyclopentane ring system and an efficient alkylation reaction of the resulting alcohol with 9H-fluoren-9-ol.
2-[Cyclopentyl[(9H-fluoren-9-ylmethoxy)carbonyl]amino]acetic acid has been shown to be a potent inhibitor against bacterial growth. It binds to bacterial topoisomerase IV enzyme, which

Formula: C₂₂H₂₃NO₄

Purity: Min. 95%

Molecular weight: 365.4 g/mol

Ref: 3D-TDC04007