The chemical substance known as methyl (2R)-2-{[(1S,3S)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]amino}-3-{[N-(morpholin-4-ylsulfonyl)-L-phenylalanyl]amino}-3-oxopropanoate, with the CAS number 134452-04-3, is a complex organic compound characterized by its intricate structure that includes multiple functional groups. It features a methyl ester group, which contributes to its solubility and reactivity. The presence of amino groups indicates potential for hydrogen bonding and interactions with biological systems, making it relevant in medicinal chemistry. The compound also contains a morpholine ring, which is often associated with enhanced pharmacological properties. Additionally, the stereochemistry indicated by the (R) and (S) designations suggests that the compound may exhibit chiral properties, influencing its biological activity and interactions. Overall, this substance is likely to be of interest in pharmaceutical research, particularly in the development of therapeutic agents targeting specific biological pathways.

PD 132002 is a renin inhibitor. Studies with PD 132002 show that the dissociation sometimes observed in studies with renin inhibitors between changes in BP (blood pressure) and PRA (plasma renin activity) may be attributed to the assay used to determine PRA.

methyl (2R)-2-{[(1S,3S)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]amino}-3-{[N-(morpholin-4-ylsulfonyl)-L-phenylalanyl]amino}-3-oxopropanoate

134452-04-3: The chemical substance known as methyl (2R)-2-{[(1S,3S)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]amino}-3-{[N-(morpholin-4-ylsulfonyl)-L-phenylalanyl]amino}-3-oxopropanoate, with the CAS number 134452-04-3, is a complex organic compound characterized by its intricate structure that includes multiple functional groups. It features a methyl ester group, which contributes to its solubility and reactivity. The presence of amino groups indicates potential for hydrogen bonding and interactions with biological systems, making it relevant in medicinal chemistry. The compound also contains a morpholine ring, which is often associated with enhanced pharmacological properties. Additionally, the stereochemistry indicated by the (R) and (S) designations suggests that the compound may exhibit chiral properties, influencing its biological activity and interactions. Overall, this substance is likely to be of interest in pharmaceutical research, particularly in the development of therapeutic agents targeting specific biological pathways.

CAS 134452-04-3

methyl (2R)-2-{[(1S,3S)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]amino}-3-{[N-(morpholin-4-ylsulfonyl)-L-phenylalanyl]amino}-3-oxopropanoate

PD 132002

Ref: TM-T28328