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CAS 134457-28-6

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PRAZARELIX

Description:
Prazarelex, identified by its CAS number 134457-28-6, is a synthetic peptide that functions as a gonadotropin-releasing hormone (GnRH) antagonist. It is primarily utilized in the field of reproductive medicine, particularly for its role in controlling ovarian stimulation during assisted reproductive technologies. The substance works by competitively inhibiting the GnRH receptors, thereby preventing the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland. This action helps to suppress premature ovulation and allows for better control over the timing of ovulation in fertility treatments. Prazarelex is characterized by its specific amino acid sequence, which contributes to its biological activity and efficacy. It is typically administered via subcutaneous injection and has a favorable pharmacokinetic profile, allowing for effective dosing regimens. As with any pharmaceutical agent, potential side effects may include injection site reactions and hormonal imbalances, necessitating careful monitoring during treatment.
Formula:C80H102ClN23O12
InChI:InChI=1/C80H102ClN23O12/c1-44(2)35-59(68(108)91-58(16-9-10-33-86-45(3)4)76(116)104-34-12-17-66(104)75(115)87-46(5)67(82)107)92-70(110)62(38-49-21-28-56(29-22-49)89-79-98-77(83)100-102-79)94-72(112)63(39-50-23-30-57(31-24-50)90-80-99-78(84)101-103-80)96-74(114)65(43-105)97-73(113)64(41-52-13-11-32-85-42-52)95-71(111)61(37-48-19-26-55(81)27-20-48)93-69(109)60(88-47(6)106)40-51-18-25-53-14-7-8-15-54(53)36-51/h7-8,11,13-15,18-32,36,42,44-46,58-66,86,105H,9-10,12,16-17,33-35,37-41,43H2,1-6H3,(H2,82,107)(H,87,115)(H,88,106)(H,91,108)(H,92,110)(H,93,109)(H,94,112)(H,95,111)(H,96,114)(H,97,113)(H4,83,89,98,100,102)(H4,84,90,99,101,103)/t46-,58+,59+,60-,61-,62-,63+,64-,65+,66+/m1/s1
Synonyms:
  • Prazarelix [inn]
  • D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-4-[(3-amino-1H-1,2,4-triazol-5-yl)amino]-L-phenylalanyl-4-[(3-amino-1H-1,2,4-triazol-5-yl)amino]-D-phenylalanyl-L-leucyl-N6-(1-methylethyl)-L-lysyl-L-prolyl-
  • PRAZARELIX
  • Azaline B
  • 134457-28-6
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  • Azaline B
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    Azaline B

    CAS:
    Azaline B is an antagonist of the gonadotropin-releasing hormone (GnRH), with an IC50 of 1.37 nM. It is utilized in research related to pathologies associated with sex hormones, ovulation induction, and male contraception.
    Formula:C80H102ClN23O12
    Color and Shape:Solid
    Molecular weight:1613.27

    Ref: TM-TP2707

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