N-Acetylheparin is a chemically modified form of heparin, a naturally occurring anticoagulant that plays a crucial role in preventing blood clot formation. It is characterized by the presence of N-acetyl groups, which enhance its solubility and bioavailability compared to standard heparin. This modification can influence its pharmacokinetic properties, making it potentially more effective in certain therapeutic applications. N-Acetylheparin retains the ability to bind to antithrombin III, thereby inhibiting thrombin and factor Xa, which are key components in the coagulation cascade. Its structure consists of a polysaccharide chain with varying degrees of sulfation, contributing to its anticoagulant activity. The substance is typically administered via injection and is used in various clinical settings, particularly in the management of thromboembolic disorders. Additionally, N-acetylheparin may exhibit anti-inflammatory properties, making it a subject of interest in research beyond anticoagulation. As with any anticoagulant, careful monitoring is essential to balance efficacy and the risk of bleeding.

N-Acetylheparin

134498-62-7: N-Acetylheparin is a chemically modified form of heparin, a naturally occurring anticoagulant that plays a crucial role in preventing blood clot formation. It is characterized by the presence of N-acetyl groups, which enhance its solubility and bioavailability compared to standard heparin. This modification can influence its pharmacokinetic properties, making it potentially more effective in certain therapeutic applications. N-Acetylheparin retains the ability to bind to antithrombin III, thereby inhibiting thrombin and factor Xa, which are key components in the coagulation cascade. Its structure consists of a polysaccharide chain with varying degrees of sulfation, contributing to its anticoagulant activity. The substance is typically administered via injection and is used in various clinical settings, particularly in the management of thromboembolic disorders. Additionally, N-acetylheparin may exhibit anti-inflammatory properties, making it a subject of interest in research beyond anticoagulation. As with any anticoagulant, careful monitoring is essential to balance efficacy and the risk of bleeding.

<p>N-Acetyl heparin is a glycosaminoglycan, which occurs in many mammalian tissues and has important anticoagulant and thrombolytic properties. The chemical structure is composed mainly of two disaccharide repeating units A and B. A is L-iduronic acid 2-suplhate linked Î±-(1,4) to 2-deoxy-2-sulfamido-D-galactose 6-sulphate, while B is D-glucuronic acid Î²-(1,4) linked to 2-deoxy-2-sulfamido-D-glucose 6-sulphate.</p>

CAS 134498-62-7

N-Acetylheparin

N-Acetyl-heparin

Ref: 3D-YA58546