CAS 1345973-53-6

APINACA

Description:

APINACA, also known as 2-[(1-amino-3-methyl-1-oxobutan-2-yl)amino]-3,3-dimethyl-1-(4-fluorobenzyl)indole, is a synthetic cannabinoid that belongs to a class of compounds designed to mimic the effects of tetrahydrocannabinol (THC), the active component of cannabis. It is characterized by its complex structure, which includes an indole core and various functional groups that contribute to its pharmacological activity. APINACA acts primarily as a potent agonist at the cannabinoid receptors, particularly CB1, leading to psychoactive effects similar to those of natural cannabinoids. Its use has been associated with various health risks, including severe psychological effects and potential toxicity. As a research chemical, it is often encountered in the context of designer drugs and has been subject to legal restrictions in many jurisdictions due to its potential for abuse and lack of safety data. The substance is typically encountered in powdered form and is often sold as a component of synthetic cannabis products.

Formula: C₂₃H₃₁N₃O

InChI: InChI=1S/C23H31N3O/c1-2-3-6-9-26-20-8-5-4-7-19(20)21(25-26)22(27)24-23-13-16-10-17(14-23)12-18(11-16)15-23/h4-5,7-8,16-18H,2-3,6,9-15H2,1H3,(H,24,27)

InChI key: InChIKey=UCTCCIPCJZKWEZ-UHFFFAOYSA-N

SMILES: N(C(=O)C=1C=2C(N(CCCCC)N1)=CC=CC2)C34CC5CC(C3)CC(C4)C5

Synonyms:

• 1-Pentyl-N-tricyclo[3.3.1.1^3,7]dec-1-yl-1H-indazole-3-carboxamide
• 1H-Indazole-3-carboxamide, 1-pentyl-N-tricyclo[3.3.1.13,7]dec-1-yl-
• 1H-Indazole-3-carboxamide, 1-pentyl-N-tricyclo[3.3.1.1^3,7]dec-1-yl-
• 1H-​ Indazole-​ 3-​ carboxamide, 1-​ pentyl-​ N-​ tricyclo[3.3.1.13,​ 7]​ dec-​ 1-​ yl-
• Akb-48
• Apinaca
• Apinica
• 1-Pentyl-N-tricyclo[3.3.1.13,7]dec-1-yl-1H-indazole-3-carboxamide

AKB-48 (APINACA; N-(1-Adamantyl)-1-pentyl-1H-indazole-3-carboxamide) 1.0 mg/ml in Acetonitrile

Controlled Product

CAS: 1345973-53-6

Color and Shape: Single Solution

Ref: 61-AMP1396.12-11

AKB-48 (APINACA; N-(1-Adamantyl)-1-pentyl-1H-indazole-3-carboxamide) 0.1 mg/ml in Acetonitrile

Controlled Product

CAS: 1345973-53-6

Color and Shape: Single Solution

Ref: 61-AMP1396.12-12

AKB-48 (APINACA), 0.1mg/ml in Methanol

Controlled Product

CAS: 1345973-53-6

Color and Shape: Single Solution

Ref: LP-AKB-1631-0.1LM

AKB-48 (APINACA; N-(1-Adamantyl)-1-pentyl-1H-indazole-3-carboxamide)

Controlled Product

CAS: 1345973-53-6

Color and Shape: Neat

Ref: 61-FOR1396.12

AKB48

Controlled Product

CAS: 1345973-53-6

Applications AKB48 is a pentyl indazole that mimics JWH 018 adamantyl carboxamide and STS-135, which are synthetic cannabinoids (CBs) that may be sold for recreational use. AKB48 is intended for research and forensic applications. Synthetic Cannabinoids

Formula: C₂₃H₃₁N₃O

Color and Shape: Neat

Molecular weight: 365.51

Ref: TR-A450100

AKB 48

Controlled Product

CAS: 1345973-53-6

AKB 48 is a synthetic cannabinoid that has been shown to bind to the CB1 receptor in mice. It has also been shown to have locomotor-stimulating effects, which are mediated by the activation of dopamine D2 receptors. AKB 48 is metabolized by cytochrome P450 enzymes and has been shown to inhibit CYP1A2, CYP2C19 and CYP3A4. This drug also interacts with many other drugs, including antidepressants, antipsychotics, antiepileptics, benzodiazepines and calcium channel blockers. In vitro studies have demonstrated that AKB 48 is metabolized by human liver microsomes as well as rat liver microsomes. The metabolism of this substance is dependent on the matrix effect and the analytical method used for detection. The acute toxicity of this drug has not yet been determined.

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 365.51 g/mol

Ref: 3D-CA175124

AKB48 (1 mg/mL in Methanol)

Controlled Product

CAS: 1345973-53-6

Formula: C₂₃H₃₁N₃O

Color and Shape: Single Solution

Molecular weight: 365.51

Ref: TR-KIT8495