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CAS 13463-41-7

:

Pyrithione zinc

Description:
Pyrithione zinc, with the CAS number 13463-41-7, is a coordination complex of zinc and pyrithione, a derivative of pyridine. It is primarily recognized for its antifungal and antibacterial properties, making it a common ingredient in various personal care products, particularly anti-dandruff shampoos and skin treatments. The compound exhibits a broad spectrum of antimicrobial activity, effectively targeting a range of fungi and bacteria. Pyrithione zinc is typically presented as a white to pale yellow solid, and it is soluble in water and alcohol, which enhances its utility in formulations. Its mechanism of action involves the disruption of cellular processes in microorganisms, leading to cell death. Additionally, it is known for its low toxicity in humans when used as directed, although it can cause skin irritation in some individuals. Due to its efficacy and safety profile, pyrithione zinc is widely used in dermatological applications and is regulated by health authorities to ensure safe usage levels in consumer products.
Formula:C10H8N2O2S2Zn
InChI:InChI=1/2C5H4NOS.Zn/c2*7-6-4-2-1-3-5(6)8;/h2*1-4H;/q2*-1;+2
InChI key:InChIKey=PICXIOQBANWBIZ-UHFFFAOYSA-N
SMILES:[Zn+2]12([O-]N3C(=[S]1)C=CC=C3)[O-]N4C(=[S]2)C=CC=C4
Synonyms:
  • (T-4)-Bis[1-(hydroxy-κO)-2(1H)-pyridinethionato-κS<sup>2</sup>]zinc
  • 1-Hydroxy-2-Pyridinthion-Zn(Ii)-Salz
  • 1-Hydroxy-2-pyridinethione, zinc salt
  • 2(1H)-Pyridinethione, 1-hydroxy-, zinc complex
  • 2-Mercaptopyridine 1-oxide zinc salt
  • 2-Mercaptopyridine N-oxide zinc salt
  • 2-Pyridinethiol 1-oxide zinc salt
  • 2-Pyridinethiol N-oxide zinc salt
  • 2-Pyridylthiol-1-oxide zinc salt
  • Af-Z
  • See more synonyms
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Found 9 products.
  • Zinc pyrithione

    CAS:
    Zinc pyrithione (OM-1563), an antibacterial and antifungal agent can disrupt membrane transport by blocking the proton pump.
    Formula:C10H8N2O2S2Zn
    Purity:99.09% - 99.47%
    Color and Shape:Off-White To Tan Powder
    Molecular weight:317.71
  • Zinc pyrithione

    CAS:
    Zinc pyrithione
    Purity:≥98%
    Molecular weight:317.71g/mol

    Ref: 54-BUP18478

    1g
    76.00€
    5g
    116.00€
    500mg
    57.00€
  • Zinc Pyrithione

    CAS:
    Formula:C10H8N2O2S2Zn
    Color and Shape:Off-White Solid
    Molecular weight:317.69

    Ref: 4Z-Z-026001

    5mg
    To inquire
    10mg
    349.00€
    25mg
    444.00€
    50mg
    635.00€
    100mg
    To inquire
  • Zinc pyrithione (Standard)

    CAS:
    Zinc pyrithione (Standard) is an analytical standard and reference sample. Zinc pyrithione (OM-1563) disrupts membrane transport by inhibiting proton pumps.
    Formula:C10H8N2O2S2Zn
    Molecular weight:317.71
  • 2-Mercaptopyridine N-Oxide Zinc Salt

    CAS:
    Formula:C10H8N2O2S2Zn
    Purity:>98.0%(T)
    Color and Shape:White to Orange to Green powder to crystal
    Molecular weight:317.69

    Ref: 3B-M0633

    25g
    62.00€
    100g
    145.00€
    500g
    446.00€
  • Pyrithione zinc

    Controlled Product
    CAS:
    Formula:C5H4NOS·Zn
    Color and Shape:Neat
    Molecular weight:317.72

    Ref: 04-C16664100

    100mg
    108.00€
  • 1-Hydroxypyridine-2-thione zinc salt

    CAS:
    Formula:C10H8N2O2S2Zn
    Purity:≥ 98.0%
    Color and Shape:White to light yellow powder
    Molecular weight:317.70

    Ref: 7W-GX2582

    25g
    60.00€
    100g
    167.00€
  • 1-Hydroxypyridine-2-thione Zinc

    Controlled Product
    CAS:
    <p>Applications 1-Hydroxypyridine-2-thione Zinc is a fungicide; used in preparation of UV antibacterial and mildew-proof topcoat with better yellowing resistance and wear resistance.<br>References Feng, S., et al.: Faming Zhuanli Shenqing, (2021);<br></p>
    Formula:C5H4NOS·Zn
    Color and Shape:Beige
    Molecular weight:317.72

    Ref: TR-H249820

    1g
    78.00€
    5g
    89.00€
    10g
    98.00€
  • 1-Hydroxypyridine-2-thione zinc

    CAS:
    <p>Zinc pyrithione is a chemical compound that can be used as an antifungal agent. It has been shown to have genotoxic activity in vitro and in vivo. Zinc pyrithione binds to the surface of the fungal cell wall and inhibits the synthesis of ergosterol, a component of the fungal cell membrane. This binding prevents the formation of an ergosterol-zinc complex with cytochrome P450 enzymes, which are required for sterol biosynthesis, leading to inhibition of energy metabolism. The model system for zinc pyrithione is a mixture of 1-hydroxypyridine-2-thione (1HP) and zinc ions in water. Some studies have shown that zinc pyrithione can cause long-term toxicity, including glycol ether toxicity, when applied topically on hair or skin. Acute toxicities may include skin irritation or contact dermatitis from shampoos containing this substance.</p>
    Formula:C10H8N2O2S2Zn
    Purity:Min. 95%
    Color and Shape:White/Off-White Solid
    Molecular weight:317.69 g/mol

    Ref: 3D-FH40903

    25g
    260.00€
    50g
    406.00€
    100g
    506.00€
    250g
    773.00€
    500g
    1,131.00€