CAS 134646-41-6

Clofarabine-5'-triphosphate

CAS: 134646-41-6

Clofarabine-5'-triphosphate is a metabolite of Clofarabine, produced via phosphorylation by deoxycytidine kinase (dCK). It exhibits cytotoxicity in cancer cells by inhibiting DNA synthesis and DNA repair.

Formula: C₁₀H₁₄ClFN₅O₁₂P₃

Color and Shape: Solid

Molecular weight: 543.62

Ref: TM-T203136

Clofarabine Triphosphate Tri(triethylamine) Salt

CAS: 134646-41-6

Formula: C₁₀H₁₄ClFN₅O₁₂P₃·3C₆H₁₅N

Molecular weight: 543.62 3x101.19

Ref: 4Z-C-11505

Clofarabine 5'-triphosphate triethylammonium salt

CAS: 134646-41-6

Clofarabine is a nucleoside analog that is used to treat various types of cancer, including leukemia, lymphoma, and solid tumours. Clofarabine has been shown to have minimal toxicity in healthy cells and is usually well tolerated by patients. It acts by inhibiting the synthesis of DNA in rapidly dividing cells. This effect can be synergistic with other anti-cancer agents such as the cytotoxic agent Bleomycin. Clofarabine binds to an intracellular target and inhibits DNA synthesis by blocking the enzyme DNA polymerase. Inhibition of this enzyme leads to cell death. Clofarabine has been tested in pediatric patients from age 1 month old up to 18 years old. The drug has been found to be safe for use in this population.

Formula: C₁₀H₁₄ClFN₅O₁₂P₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 543.62 g/mol

Ref: 3D-NC15333

Clofarabine Triphosphate Triethylamine Salt

Controlled Product

CAS: 134646-41-6

Formula: C₁₀H₁₄ClFN₅O₁₂P₃•x(C₆H₁₅N)

Color and Shape: Neat

Molecular weight: 543.62 + x(101.19)

Ref: TR-C586900

Clofarabine Triphosphate-13C,15N3 Triethylamine Salt

Controlled Product

CAS: 134646-41-6

Formula: C₉CH₁₄ClFN₂N₃O₁₂P₃•x(C₆H₁₅N)

Color and Shape: Neat

Molecular weight: 547.59 + x(101.19)

Ref: TR-C586902

Clofarabine Triphosphate

CAS: 134646-41-6

Formula: C₁₀H₁₄ClFN₅O₁₂P₃

Molecular weight: 543.61

Ref: ST-EA-CP-C83005