CAS 1346599-56-1

Tolvaptan Open Ring Ketoacid (4-(5-chloro-2-(2-methyl-4-(2-methylbenzamido)benzamido)phenyl)-4-oxobutanoic acid)

CAS: 1346599-56-1

Aromatic cyclic amides (including cyclic carbamates) and their derivatives; salts thereof

Formula: C₂₆H₂₃ClN₂O₅

Color and Shape: Off-White Solid

Molecular weight: 478.12955

Ref: 45-1A04720

Tolvaptan Impurity 1 (DM-4103)

CAS: 1346599-56-1

Formula: C₂₆H₂₃ClN₂O₅

Color and Shape: White To Off-White Solid

Molecular weight: 478.93

Ref: 4Z-T-699

Tolvaptan γ-Oxobutanoic Acid Impurity

Controlled Product

CAS: 1346599-56-1

Formula: C₂₆H₂₃ClN₂O₅

Color and Shape: Neat

Molecular weight: 478.924

Ref: TR-T536665

Tolvaptan gamma-oxobutanoic acid impurity

CAS: 1346599-56-1

Tolvaptan is a drug that is used for the treatment of hyponatremia. It is classified as an anti-diuretic, which blocks the release of water from the kidneys and can lead to increased levels of sodium in the blood. Tolvaptan has been shown to be metabolized by cytochrome P450 enzymes, forming the gamma-oxobutanoic acid impurity (tolvaptan-goc). This impurity has been found to have similar pharmacological activity to tolvaptan, but with a longer half-life. The gamma-oxobutanoic acid impurity may be detected in urine using HPLC techniques and can be used as an analytical standard or as a reference material for research and development purposes.

Formula: C₂₆H₂₃ClN₂O₅

Purity: Min. 95%

Molecular weight: 478.90 g/mol

Ref: 3D-WDC59956

Tolvaptan Impurity 1

CAS: 1346599-56-1

Formula: C₂₆H₂₃ClN₂O₅

Molecular weight: 478.93

Ref: ST-EA-CP-T26011