CAS 1346603-41-5

N-NitrosodiethylaMine-d4

Description:

N-Nitrosodiethylamine-d4 is a deuterated derivative of N-nitrosodiethylamine (NDEA), a well-known nitrosamine compound. It is characterized by the presence of a nitroso group (-N=O) attached to a diethylamine moiety, where the hydrogen atoms in the ethyl groups are replaced by deuterium, a stable isotope of hydrogen. This modification allows for enhanced tracking and analysis in various chemical and biological studies. N-Nitrosodiethylamine is recognized for its potential carcinogenic properties, particularly in animal studies, and is often used in research to understand mechanisms of carcinogenesis. The deuterated form, while retaining similar chemical properties, may exhibit differences in reactivity and stability due to the presence of deuterium. It is typically handled with caution in laboratory settings, adhering to safety protocols due to its toxicological implications. As with many nitrosamines, it is important to consider its environmental impact and regulatory status in research and industrial applications.

Formula: C₄H₁₀N₂O

Synonyms:

• N,N-DiethylnitrosoaMine-d4
• DiethylnitrosoaMine-d4
• NitrosodiethylaMin-d4
• N-Nitroso-N,N-diethylaMine-d4
• N-NitrosodiethylaMine-d4
• DENA-d4
• DEN-d4
• [2H4]-N-Nitrosodiethylamine
• DiethylnitrosaMine-d4
• NDEA-d4
• N-Ethyl-N-nitrosoethanaMine-d4
• WBNQDOYYEUMPFS-KHORGVISSA-N
• NSC 132-d4

N-Nitroso Melphalan EP Impurity K-d4 (NDEA-d4)

CAS: 1346603-41-5

Formula: C₄H₆D₄N₂O

Molecular weight: 106.16

Ref: 4Z-M-8545

N-Nitrosodiethylamine-d4

Controlled Product

CAS: 1346603-41-5

Stability Light Sensitive
Applications Isotope labelled N-Nitrosodiethylamine (N525465) (DEN) is a widely occurring nitrosamine that is one of the most important environmental carcinogens (1) primarily inducing tumors of liver (2,3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.NDMA and NDEA were found as an impurity in generic versions of valsartan, losartan and irbesartan.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References 1. Farber, E. et al.: Cancer Res. 1984 Oct;44(10):4217-23.2. el-Demerdash, E. et al.: Anticancer Res. 2002 Mar-Apr;22(2A):977-84.3. Kweon, S. et al.: Life Sci. 2003 Sep 26;73(19):2515-26.

Formula: C₄₂H₄H₆N₂O

Color and Shape: Colourless To Yellow

Molecular weight: 106.16

Ref: TR-N525467

N-Nitrosodiethylamine-d4 + Nitrosobis(2-hydroxyethyl)amine-d8 (Mixture) (1mg/mL in Methanol)

Controlled Product

CAS: 1173019-53-8, 1346603-41-5

Formula: MixtureVisitourWebsite

Color and Shape: Mixture

Molecular weight: Mixture - Visit our Website

Ref: TR-KIT6528