CAS 1346623-17-3

(2R,3S)-2-[4-(Cyclopentylamino)phenyl]-1-(2-fluoro-6-methylbenzoyl)-N-[4-methyl-3-(trifluoromethyl)phenyl]-3-piperidinecarboxamide

Description:

The chemical substance with the name "(2R,3S)-2-[4-(Cyclopentylamino)phenyl]-1-(2-fluoro-6-methylbenzoyl)-N-[4-methyl-3-(trifluoromethyl)phenyl]-3-piperidinecarboxamide" and CAS number "1346623-17-3" is a complex organic compound characterized by its multi-functional structure. It features a piperidine ring, which is a six-membered nitrogen-containing heterocycle, and incorporates various aromatic groups, including a cyclopentylamino-substituted phenyl moiety and a trifluoromethyl-substituted phenyl group. The presence of a fluorine atom and a methyl group on the benzoyl moiety contributes to its unique chemical properties, potentially influencing its biological activity and solubility. This compound may exhibit specific interactions with biological targets, making it of interest in medicinal chemistry. Its stereochemistry, indicated by the (2R,3S) configuration, suggests that it may have distinct pharmacological properties based on its three-dimensional arrangement. Overall, this substance represents a class of compounds that could be explored for therapeutic applications, particularly in the fields of oncology or neurology, depending on its mechanism of action.

Formula: C₃₃H₃₅F₄N₃O₂

InChI: InChI=1S/C33H35F4N3O2/c1-20-12-15-25(19-27(20)33(35,36)37)39-31(41)26-10-6-18-40(32(42)29-21(2)7-5-11-28(29)34)30(26)22-13-16-24(17-14-22)38-23-8-3-4-9-23/h5,7,11-17,19,23,26,30,38H,3-4,6,8-10,18H2,1-2H3,(H,39,41)/t26-,30-/m0/s1

InChI key: InChIKey=PUKBOVABABRILL-YZNIXAGQSA-N

SMILES: C(=O)(N1[C@H]([C@@H](C(NC2=CC(C(F)(F)F)=C(C)C=C2)=O)CCC1)C3=CC=C(NC4CCCC4)C=C3)C5=C(C)C=CC=C5F

Synonyms:

• CCX 168
• (2R,3S)-2-[4-(Cyclopentylamino)phenyl]-1-(2-fluoro-6-methylbenzoyl)-N-[4-methyl-3-(trifluoromethyl)phenyl]-3-piperidinecarboxamide
• Avacopan
• (2R,3S)-2-[4-(cyclopentylamino)phenyl]-1-(2-fluoro-6-methylbenzoyl)-N-[4-methyl3-(trifluoromethyl)phenyl]piperidine-3-carboxamide
• 3-Piperidinecarboxamide, 2-[4-(cyclopentylamino)phenyl]-1-(2-fluoro-6-methylbenzoyl)-N-[4-methyl-3-(trifluoromethyl)phenyl]-, (2R,3S)-

Avacopan

CAS: 1346623-17-3

Avacopan

Purity: ≥98%

Molecular weight: 581.64g/mol

Ref: 54-BUP01579

Avacopan

CAS: 1346623-17-3

Formula: C₃₃H₃₅F₄N₃O₂

Molecular weight: 581.66

Ref: 4Z-A-369001

Avacopan

CAS: 1346623-17-3

Avacopan (CCX168) is a C5aR antagonist with selective and oral activity. Avacopan can be used to treat ANCA-related vasculitis. Cost-effective and quality-assured.

Formula: C₃₃H₃₅F₄N₃O₂

Purity: 99.47% - 99.9%

Color and Shape: Solid

Molecular weight: 581.64

Ref: TM-T8223

Avacopan

CAS: 1346623-17-3

Formula: C₃₃H₃₅F₄N₃O₂

Color and Shape: Neat

Ref: TR-A245770