CAS 134678-17-4: Lamivudine

Description: Lamivudine is an antiretroviral medication primarily used in the treatment of HIV/AIDS and chronic hepatitis B infection. It belongs to the class of nucleoside reverse transcriptase inhibitors (NRTIs) and functions by inhibiting the reverse transcriptase enzyme, which is crucial for viral replication. The chemical formula of Lamivudine is C8H11N3O3S, and it features a thiophenecarboxamide structure, which contributes to its pharmacological activity. Lamivudine is typically administered orally and is well-absorbed in the gastrointestinal tract, with a favorable safety profile. Common side effects may include headache, fatigue, and gastrointestinal disturbances. It is important to note that Lamivudine is often used in combination with other antiretroviral agents to enhance efficacy and reduce the risk of resistance. The substance is classified as a prescription medication and is included in various treatment guidelines for managing HIV and hepatitis B. Its effectiveness and safety have been well-documented in clinical studies, making it a vital component of antiviral therapy.

Formula: C₈H₁₁N₃O₃S

InChI: InChI=1S/C8H11N3O3S/c9-5-1-2-11(8(13)10-5)6-4-15-7(3-12)14-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7+/m0/s1

InChI key: InChIKey=JTEGQNOMFQHVDC-NKWVEPMBSA-N

SMILES: O=C1N=C(N)C=CN1C2OC(SC2)CO

Synonyms:

• (-) 2'-Deoxy-3'-thiacytidine
• (-)-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cystosine
• (-)-2¢ -Deoxy-3¢ -Thiacytidine
• (-)-Bch-189
• (-)Ngpb-21
• (2R-cis)-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
• (2R-cis)-4-amino-1-
• 1,3-Oxathiolane, 2(1H)-pyrimidinone deriv.
• 2(1H)-Pyrimidinone, 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-
• 2(1H)-Pyrimidinone,4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-,(2R-cis)-
• 2-Hydroxymethyl-5-(cytosin-1-yl)-1,3-oxathiolane
• 3'-Thia-2',3'-Dideoxcytidine
• 3TC
• 3¢ -Thia-2¢ ,3¢ -Dideoxycytidine
• 4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
• 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
• 4-amino-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
• <span class="text-smallcaps">L</span>-SddC
• Epivir
• Epivir HBV
• Gr 109714X
• Gr109714X
• Hepitec
• Heptodin
• Heptovir
• Hiviral
• Lamidine
• Lamivir
• Virolam
• Zeffix
• Zefix
• cis(-)-2-Hydroxymethyl-5-(cytosin-1-yl)-1,3-oxathiolane
• β-<span class="text-smallcaps">L</span>-2′,3′-Dideoxy-3′-thiacytidine
• β-<span class="text-smallcaps">L</span>-3′-Thia-2′,3′-dideoxycytidine
• 3￠-thia-2￠,3￠-dideoxycytidine
• (-)-2￠-deoxy-3￠-thiacytidine

Lamivudine Mono POC Impurity

CAS: 134678-17-4

• Formula: C₂₃H₃₃N₈O₁₀PS
• Molecular weight: 644.60

Lamivudine

CAS: 134678-17-4

Lamivudine (BCH-189) is a reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom …

• Formula: C₈H₁₁N₃O₃S
• Purity: 100% - 99.56%
• Color and Shape: White Crystalline Powder
• Molecular weight: 229.26

Lamivudine-13C1,d2

CAS: 134678-17-4

Stability Hygroscopic Applications Lamivudine-13C1,d2, is the labeled analogue of Lamivudine (L172502). A reverse transcriptase inhibitor. …

• Formula: C₇₁₃CH₉D₂N₃O₃S
• Color and Shape: White Powder
• Molecular weight: 232.26

Lamivudine

CAS: 134678-17-4

Applications Lamivudine is a potent nucleoside reverse transcriptase inhibitor. Antiviral. Lamivudine has been used for …

• Formula: C₈H₁₁N₃O₃S
• Color and Shape: White
• Molecular weight: 229.26

Lamivudine

CAS: 134678-17-4

Anti-viral; reverse transcriptase inhibitor

• Formula: C₈H₁₁N₃O₃S
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 229.26 g/mol

Lamivudine - Bio-X ™

CAS: 134678-17-4

Lamivudine (commonly called 3TC) is a potent nucleoside analogue reverse transcriptase inhibitor. It is one …

• Formula: C₈H₁₁N₃O₃S
• Purity: Min. 95%
• Molecular weight: 229.26 g/mol

Lamivudine Dimer

CAS: 134678-17-4

Applications Lamivudine Dimer is an impurity of Lamivudine (L172500); a potent nucleoside reverse transcriptase inhibitor …

• Formula: C₁₇H₂₂N₆O₆S₂
• Color and Shape: Neat
• Molecular weight: 470.523