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CAS 134790-39-9

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Cytidine, 2′-deoxy-2′,2′-difluoro-, 3′,5′-dibenzoate

Description:
Cytidine, 2′-deoxy-2′,2′-difluoro-, 3′,5′-dibenzoate, with CAS number 134790-39-9, is a modified nucleoside derivative that features a deoxyribose sugar backbone with two fluorine atoms substituted at the 2' position. This compound is characterized by its dibenzoate ester groups at the 3' and 5' positions, which enhance its lipophilicity and potentially influence its biological activity. The presence of fluorine atoms can alter the compound's stability and interaction with biological targets, making it of interest in medicinal chemistry and drug design. Typically, such modifications can affect the nucleoside's ability to participate in nucleic acid synthesis and its overall pharmacokinetic properties. The compound may exhibit unique properties in terms of solubility, reactivity, and binding affinity to nucleic acid structures, which could be leveraged in therapeutic applications, particularly in antiviral or anticancer strategies. As with many nucleoside analogs, its biological activity would need to be evaluated through experimental studies to ascertain its potential uses in research or clinical settings.
Formula:C23H19F2N3O6
InChI:InChI=1S/C23H19F2N3O6/c24-23(25)18(34-20(30)15-9-5-2-6-10-15)16(13-32-19(29)14-7-3-1-4-8-14)33-21(23)28-12-11-17(26)27-22(28)31/h1-12,16,18,21H,13H2,(H2,26,27,31)/t16-,18-,21-/m1/s1
InChI key:InChIKey=ZPUUYUUQQGBHBU-HGHGUNKESA-N
SMILES:FC1(F)[C@@H](O[C@H](COC(=O)C2=CC=CC=C2)[C@H]1OC(=O)C3=CC=CC=C3)N4C(=O)N=C(N)C=C4
Synonyms:
  • 2',2'-Difluoro-3',5'-dibenzoyl-2'-deoxycytidine
  • 2',2'-Difluoro-3',5'-dibenzoyl-2'-deoxycytidine (beta isomer)
  • 2'-deoxy-2',2'-difluoro-3',5'-bis-O-(phenylcarbonyl)cytidine
  • 2,2-Difluoro-2-Deoxycytidine-3,5-Dibenzoate
  • 3',5'-Di-O-benzoyl-2',2'-difluoro-2'-deoxy cytidine
  • 3′,5′-Di-O-benzoyl-2′-deoxy-2′,2′-difluorocytidine
  • Cytidine, 2′-deoxy-2′,2′-difluoro-, 3′,5′-dibenzoate
  • T9
  • T9:2’,2’-Difluoro-2’-deoxycytidine-3’,5’-dibenzoate
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