CAS 1348536-59-3

Axitinib Impurity 7

CAS: 1348536-59-3

Formula: C₂₂H₁₈N₄O₃S

Color and Shape: Pale Yellow Solid

Molecular weight: 418.47

Ref: 4Z-A-188010

Axitinib Sulfone

CAS: 1348536-59-3

Formula: C₂₂H₁₈N₄O₃S

Molecular weight: 418.47

Ref: ST-EA-CP-A34010

N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfonyl]benzamide

Controlled Product

CAS: 1348536-59-3

Applications N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfonyl]benzamide (Axitinib sulfone) is an impurity of axitinib (A794650), a tyrosine kinase inhibitor and is used in cancer therapy.
References Wasser, K., et al.: Eur. Radiol., 13, 80 (2003), Park, J., et al.: Clin. Cancer Res., 8, 1172 (2002), Bergers, G., et al.: J. Clin. Invest., 111, 1287 (2003),

Formula: C₂₂H₁₈N₄O₃S

Color and Shape: Neat

Molecular weight: 418.468

Ref: TR-M330455

N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfonyl]benzamide

CAS: 1348536-59-3

N-Methyl-2-[(3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl)sulfonyl]benzamide is a potent and selective inhibitor of the protease cathepsin B. It also inhibits protein interactions, such as the binding of amyloid β to its receptor. N-Methyl-2-[(3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl)sulfonyl]benzamide is a ligand for the human receptor, FPRL1. It has been used in research as a tool for studying protein interactions and antibody production. The product is available in pure form with > 98% purity.br>br> N-[3-(4'-Fluoro[1,1'-biphenyl]-4-sulfony

Formula: C₂₂H₁₈N₄O₃S

Purity: Min. 95%

Molecular weight: 418.5 g/mol

Ref: 3D-YDC53659