CAS 134869-15-1

Lactimidomycin

Description:

Lactimidomycin is a natural product with notable antibacterial properties, primarily derived from the fermentation of certain Streptomyces species. It is classified as a polyketide and exhibits a complex structure that includes a lactam ring, contributing to its biological activity. The compound has garnered interest for its potential use in treating bacterial infections, particularly those caused by resistant strains. Lactimidomycin functions by inhibiting protein synthesis, which disrupts bacterial growth and proliferation. Its mechanism of action involves binding to the ribosomal subunit, thereby interfering with the translation process. In addition to its antibacterial effects, research has indicated that Lactimidomycin may possess antitumor properties, making it a candidate for further pharmacological exploration. The substance is characterized by its specific molecular weight and formula, which are essential for understanding its reactivity and interactions in biological systems. As with many natural products, the study of Lactimidomycin continues to evolve, with ongoing research aimed at elucidating its full therapeutic potential and optimizing its use in clinical settings.

Formula: C₂₆H₃₅NO₆

InChI: InChI=1/C26H35NO6/c1-17-10-8-6-4-5-7-9-11-25(32)33-26(17)19(3)12-18(2)22(29)16-21(28)13-20-14-23(30)27-24(31)15-20/h4,6,8-12,17-18,20-21,26,28H,5,7,13-16H2,1-3H3,(H,27,30,31)/b6-4-,10-8-,11-9-,19-12-

SMILES: CC1C=CC=CCCC=CC(=O)OC1/C(=C\C(C)C(=O)CC(CC1CC(=NC(=O)C1)O)O)/C

Synonyms:

• 2,6-Piperidinedione, 4-(2-hydroxy-5-methyl-7-(3-methyl-12-oxooxacyclododeca-4,6,10-trien-2-yl)-4-oxo-6-octenyl)-
• 2,6-Piperidinedione, 4-(2-hydroxy-5-methyl-7-(3-methyl-12oxooxacyclododeca-4,6,10-trien-2-yl)-4-oxo-6-octenyl)-
• 4-{(6Z)-2-hydroxy-5-methyl-7-[(4Z)-3-methyl-12-oxooxacyclododeca-4,6,10-trien-2-yl]-4-oxooct-6-en-1-yl}piperidine-2,6-dione

Lactimidomycin

CAS: 134869-15-1

Lactimidomycin from Streptomyces blocks eukaryotic translation and RNA viruses, fights tumors, IC50: 37.82 nM.

Formula: C₂₆H₃₅NO₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 457.56

Ref: TM-T15703

Lactimidomycin

CAS: 134869-15-1

Lactimidomycin is a peptide antibiotic that blocks the activity of ion channels, which are proteins that control the flow of ions across cell membranes. Lactimidomycin binds to specific ligands on the surface of cells and inhibits membrane depolarization. It has been shown to inhibit the activity of calcium-gated potassium channels, hyperpolarize nerve cells, and inhibit neuronal excitability. Lactimidomycin has also been shown to be an inhibitor of protein interactions with antibodies and other cellular factors. This drug can be used as a research tool for studying protein interactions in living cells. Lactimidomycin is available in high purity and at CAS No. 134869-15-1.

Formula: C₂₆H₃₅NO₆

Purity: Min. 95%

Molecular weight: 457.6 g/mol

Ref: 3D-JFA86915