CAS 134874-49-0

Methoxypolyethylene glycol thiol

Description:

Methoxypolyethylene glycol thiol, often abbreviated as mPEG-thiol, is a synthetic polymer characterized by the presence of a methoxy group and a thiol functional group. This compound is a derivative of polyethylene glycol (PEG), which is known for its biocompatibility and hydrophilicity. The thiol group (-SH) provides reactive sites for various chemical modifications, making mPEG-thiol useful in bioconjugation and drug delivery applications. Its structure typically consists of a polyethylene glycol backbone with a terminal methoxy group and a thiol group, which enhances its solubility in aqueous environments. The presence of the thiol group allows for the formation of disulfide bonds, facilitating the creation of cross-linked networks or conjugates with proteins and other biomolecules. Additionally, mPEG-thiol is often employed in the development of hydrogels, nanoparticles, and other materials in biomedical applications, including tissue engineering and targeted drug delivery systems. Its versatility and functional properties make it a valuable compound in both research and industrial settings.

Formula: (C₂H₄O)nC₃H₈OS

InChI: InChI=1S/C5H12O2S/c1-6-2-3-7-4-5-8/h8H,2-5H2,1H3

InChI key: InChIKey=CDBORKXXLPAUKJ-UHFFFAOYSA-N

SMILES: C(OCCS)COC

Synonyms:

• mPEG-SH
• Poly(oxy-1,2-ethanediyl), α-(2-mercaptoethyl)-ω-methoxy-
• Polyethylene glycol 2-mercaptoethyl methyl ether
• α-Methyl-ω-(2-mercaptoethoxy)poly(oxy-1,2-ethanediyl)
• MeO-PEG-SH

mPEG12-SH

CAS: 134874-49-0

Formula: C₆H₁₆O₂S

Purity: 97%

Color and Shape: Solid

Molecular weight: 152.2550

Ref: IN-DA009C2A

O-(2-Mercaptoethyl)-O'-Methylpolyethylene Glycol

CAS: 134874-49-0

O-(2-Mercaptoethyl)-O'-Methylpolyethylene Glycol

Purity: average M.W. 2000

Ref: 54-OR1014510

m-PEG-thiol (MW 2000)

CAS: 134874-49-0

Purity: 98%

Ref: 10-F554850

m-dPEG®12-Thiol

CAS: 134874-49-0

m-dPEG®12-Thiol is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. m-dPEG®12-Thiol is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Formula: C₃₇H₆₉N₃O₁₆S

Purity: Min. 95%

Molecular weight: 844.02 g/mol

Ref: 3D-DPG-6120