CAS 134878-17-4

(2S)-N-[(2S,3R,4S,5S)-3,4-dihydroxy-5-{[(2S)-3-methyl-2-{[methyl(pyridin-2-ylmethyl)carbamoyl]amino}butanoyl]amino}-1,6-diphenylhexan-2-yl]-3-methyl-2-{[methyl(pyridin-2-ylmethyl)carbamoyl]amino}butanamide (non-preferred name)

Description:

The chemical substance with the name "(2S)-N-[(2S,3R,4S,5S)-3,4-dihydroxy-5-{[(2S)-3-methyl-2-{[methyl(pyridin-2-ylmethyl)carbamoyl]amino}butanoyl]amino}-1,6-diphenylhexan-2-yl]-3-methyl-2-{[methyl(pyridin-2-ylmethyl)carbamoyl]amino}butanamide" and CAS number "134878-17-4" is a complex organic molecule characterized by multiple stereocenters and functional groups. It features a backbone that includes a hexane chain with various substituents, including hydroxyl groups and amide linkages, which contribute to its biological activity. The presence of pyridine rings suggests potential interactions with biological targets, possibly influencing its pharmacological properties. The stereochemistry indicated by the (S) and (R) designations is crucial for its activity, as the three-dimensional arrangement of atoms can significantly affect how the molecule interacts with enzymes or receptors. This compound may be of interest in medicinal chemistry, particularly in the development of therapeutics, due to its intricate structure and potential bioactivity.

Formula: C₄₄H₅₈N₈O₆

InChI: InChI=1/C44H58N8O6/c1-29(2)37(49-43(57)51(5)27-33-21-13-15-23-45-33)41(55)47-35(25-31-17-9-7-10-18-31)39(53)40(54)36(26-32-19-11-8-12-20-32)48-42(56)38(30(3)4)50-44(58)52(6)28-34-22-14-16-24-46-34/h7-24,29-30,35-40,53-54H,25-28H2,1-6H3,(H,47,55)(H,48,56)(H,49,57)(H,50,58)/t35-,36-,37-,38-,39-,40+/m0/s1

Synonyms:

• (2S)-N-[(2S,3R,4S,5S)-3,4-Dihydroxy-5-{[(2S)-3-methyl-2-{[methyl(pyridin-2-ylmethyl)carbamoyl]amino}butanoyl]amino}-1,6-diphenylhexan-2-yl]-3-methyl-2-{[methyl(pyridin-2-ylmethyl)carbamoyl]amino}butanamide (non-preferred name)
• (2(S),5(S))-1,2,5,6-Tetradeoxy-2,5-bis((3-methyl-2-(((methyl(2-pyrimidinylmethyl)amino)carbonyl)amino)-1-oxobutyl)amino)-1,6-diphenyl-L-altritol
• 134878-17-4
• Abbott 77003

A 77003

CAS: 134878-17-4

A 77003 is a HIV-1 protease inhibitor. A77003 impairs HIV-1 protease-mediated Gag processing.

Formula: C₄₄H₅₈N₈O₆

Color and Shape: Solid

Molecular weight: 794.98

Ref: TM-T26446