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CAS 134887-79-9

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altromycin G

Description:
Altromycin G is a natural antibiotic compound belonging to the class of macrolides, which are characterized by their large lactone rings. It is produced by certain strains of the bacterium Streptomyces, known for their ability to synthesize a variety of bioactive secondary metabolites. Altromycin G exhibits antibacterial properties, particularly against Gram-positive bacteria, making it of interest in the field of medicinal chemistry and pharmacology. The compound's mechanism of action typically involves inhibition of protein synthesis by binding to the bacterial ribosome, thereby interfering with the translation process. In terms of its chemical structure, altromycin G features a complex arrangement of carbon, hydrogen, and oxygen atoms, contributing to its biological activity and stability. Research into altromycin G and similar compounds continues to explore their potential therapeutic applications, especially in an era of increasing antibiotic resistance. Overall, altromycin G represents a significant example of the diverse chemical entities derived from natural sources that hold promise for future drug development.
Formula:C45H55NO18
InChI:InChI=1/C45H55NO18/c1-16-32(48)25(56-7)14-28(60-16)63-40-18(3)59-26(15-43(40,5)46)20-10-11-21-29(35(20)51)36(52)30-22(34(21)50)12-23(31-24(47)13-27(62-38(30)31)44(6)19(4)64-44)45(55,42(54)58-9)41-37(53)39(57-8)33(49)17(2)61-41/h10-13,16-19,25-26,28,32-33,37,39-41,48-49,51,53,55H,14-15,46H2,1-9H3
Synonyms:
  • methyl [10-{4-amino-5-[(5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy]-4,6-dimethyltetrahydro-2H-pyran-2-yl}-2-(2,3-dimethyloxiran-2-yl)-11-hydroxy-4,7,12-trioxo-7,12-dihydro-4H-naphtho[2,3-h]chromen-5-yl](3,5-dihydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)hydroxyacetate (non-preferred name)
  • Altromycin G
  • D-glycero-D-manno-Octonic acid, 2-C-(10-(3-amino-2,3,6-trideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-D-ribo-hexopyranosyl)-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-2-(2,3-dimethyloxiranyl)-7,12-dihydro-11-hydroxy-4,7,12-trioxo-4H-anthra(1,2-b)pyran-4-yl)-3,7-anhydro-8-deoxy-5-O-methyl-, methyl ester, (2xi)-
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