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CAS 13489-75-3

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3A,5B-tetrahydroaldosterone

Description:
3A,5B-tetrahydroaldosterone, with the CAS number 13489-75-3, is a steroid hormone that is a derivative of aldosterone, which plays a crucial role in regulating sodium and potassium levels in the body. This compound is characterized by its tetrahydro structure, indicating that it has undergone hydrogenation, resulting in a saturated ring system. It is typically classified as a mineralocorticoid, influencing electrolyte balance and fluid homeostasis. The chemical structure features multiple hydroxyl groups, which contribute to its solubility and biological activity. As a steroid, it exhibits lipophilic properties, allowing it to easily cross cell membranes and bind to specific receptors, thereby modulating gene expression and physiological responses. Its biological significance is primarily linked to its effects on renal function and blood pressure regulation. While specific pharmacological data may vary, compounds in this class are often studied for their potential therapeutic applications in conditions related to fluid retention and hypertension.
Formula:C21H32O5
InChI:InChI=1/C21H32O5/c1-20-7-6-12(23)8-11(20)2-3-13-14-4-5-15(16(24)10-22)21(14)9-17(18(13)20)26-19(21)25/h11-15,17-19,22-23,25H,2-10H2,1H3/t11-,12-,13+,14+,15-,17+,18-,19?,20+,21-/m1/s1
Synonyms:
  • Tetrahydroaldosterone
  • 3alpha,5alpha-Tetrahydroaldosterone
  • 3alpha,5beta-Tetrahydroaldosterone
  • Pregnan-20-one, 11,18-epoxy-3,18,21-trihydroxy-, (3alpha,5beta,11beta)-
  • (3Alpha,5Beta,11Beta)-3,18,21-Trihydroxy-11,18-Epoxypregnan-20-One
  • 5β-Pregnan-11β,18-epoxy-3α,18,21-triol-20-one
  • Pregnan-20-one, 11,18-epoxy-3,18,21-trihydroxy-, (3α,5β,11β)-
  • 3ALPHA,5B-Tetrahydroaldosterone
  • 11β,18-Epoxy-3α,18,21-trihydroxy-5β-pregnan-20-one
  • "3-α,5-β-Tetrahydroaldosterone-[D6]"
  • See more synonyms
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