CAS 1349723-93-8

Elacestrant DiHCl

CAS: 1349723-93-8

Formula: C₃₀H₃₈N₂O₂·2HCl

Molecular weight: 458.65 2*36.46

Ref: 4Z-E-242001

Elacestrant dihydrochloride

CAS: 1349723-93-8

Elacestrant dihydrochloride

Purity: ≥98%

Molecular weight: 531.56g/mol

Ref: 54-BUP12719

Elacestrant dihydrochloride

CAS: 1349723-93-8

Elacestrant dihydrochloride (DA-DKRAD1901 dihydrochloride) is an orally available selective estrogen receptor degrader with IC50s of 48 for ERα and 870 nM for

Formula: C₃₀H₄₀Cl₂N₂O₂

Purity: 99.59% - >99.99%

Color and Shape: Solid

Molecular weight: 531.56

Ref: TM-T13675

Elacestrant dihydrochloride

Controlled Product

CAS: 1349723-93-8

Elacestrant dihydrochloride is a potential drug for the treatment of breast cancer. This agent has been shown to inhibit the activity of CDK4/6, which are enzymes that regulate the cell cycle and prevent progression from G1 to S phase. Elacestrant dihydrochloride also causes apoptosis in tumor cells by binding to death receptors, causing them to trigger the release of proteins that activate apoptosis. The uptake of elacestrant dihydrochloride into tumor cells is increased by epidermal growth factor (EGF) and other receptor binding drugs. A study found that elacestrant dihydrochloride at a dose of 100 mg/kg was effective in reducing tumor growth in xenograft mice models when combined with palbociclib.

Formula: C₃₀H₄₀Cl₂N₂O₂

Purity: Min. 95%

Molecular weight: 531.56 g/mol

Ref: 3D-FE177759