CAS 135-09-1
:hydroflumethiazide
Description:
Hydroflumethiazide is a thiazide diuretic commonly used in the treatment of hypertension and edema associated with various medical conditions. It functions by inhibiting sodium reabsorption in the distal convoluted tubule of the nephron, leading to increased excretion of sodium and water, which helps to lower blood pressure and reduce fluid retention. The chemical formula of hydroflumethiazide is C8H8ClN3O4S, and it features a sulfonamide group, a thiazide ring, and a chloro substituent, contributing to its pharmacological activity. This compound is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing in many cases. Hydroflumethiazide may cause side effects such as electrolyte imbalances, dehydration, and gastrointestinal disturbances. As with other diuretics, monitoring of renal function and electrolyte levels is essential during treatment. Its efficacy and safety profile make it a valuable option in managing cardiovascular conditions, although it should be used with caution in patients with certain pre-existing health issues.
Formula:C8H8F3N3O4S2
InChI:InChI=1/C8H8F3N3O4S2/c9-8(10,11)4-1-5-7(2-6(4)19(12,15)16)20(17,18)14-3-13-5/h1-2,13-14H,3H2,(H2,12,15,16)
InChI key:InChIKey=DMDGGSIALPNSEE-UHFFFAOYSA-N
SMILES:O=S1(=O)C=2C(=CC(C(F)(F)F)=C(S(N)(=O)=O)C2)NCN1
Synonyms:- 1,1-Dioxo-6-(trifluoromethyl)-1,2,3,4-tetrahydro-1λ6,2,4-benzothiadiazine-7-sulfonamide
- 1,1-Dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide
- 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3,4-dihydro-6-(trifluoromethyl)-, 1,1-dioxide
- 3,4-Dihydro-6-(trifluoromethyl)-2H-1,2,4-
- 3,4-Dihydro-6-trifluoromethyl-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
- 3,4-Dihydro-6-trifluoromethyl-2H-1,2,4-benzothiazide-7-sulfonamide 1,1-dioxide
- 3,4-Dihydro-6-trifluoromethyl-7-sulfamoylbenzo-1,2,4-thiadiazine 1,1-dioxide
- 3,4-Dihydro-7-sulfamoyl-6-trifluoromethyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
- 3,4-Dihydro-7-sulfamyl-6-trifluoromethyl-1,2,4-benzothiadiazine 1,1-dioxide
- 3,4-Dihydro-7-sulfamyl-6-trifluoromethyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
- 6-(trifluoromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
- 6-Trifluoromethyl-3,4-dihydro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
- 6-Trifluoromethyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide
- 7-Sulfamyl-6-trifluoromethyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide
- Benzothiodiazine(2H-1,2,4)-7-Sulfonamide, 3,4-Dihydro-6-Trifluoromethyl)-1,1-Dioxide
- Bristab
- Bristurin
- Di-Ademil
- Dihydroflumethiazide
- Diucardin
- Diumide K
- Diuredemina
- Diurometon
- Elodrine
- Finuret
- Flutizide
- Glomerulin
- Hidroalogen
- Hidroflumetiazid
- Hidroflumetiazida
- Hydol
- Hydrenox
- Hydroflumethiazid
- Leodrine
- Metflorylthiazidine
- Methforylthiazidine
- NaClex
- NaClex (Glaxo)
- Nsc 44627
- Olmagran
- Rodiuran
- Rontyl
- Saluron
- Salutensin
- Sisuril
- Spandiuril
- Trifluoromethylhydrothiazide
- Vergonil
- Hydroflumethiazide Q: What is the CAS Number of
- Hydroflumethiazide
- 6
- 6-trifluoromethyl-3,4-dihydro-7-sulfamoyl-2h-1,2,4-benzothiadiazine1,1-dioxi
- 3,4-Dihydro-6-(trifluoromethyl)-2H-1,2,4-Benzothiadiazine-7-sulphonamide-1,1-dioxide95+%
- Hydroumethiazide (200 mg)
- Hydroflumethiazide (1322007)
- 7-sulfamyl-6-trifluoromethyl-3,4-dihydro-1,2,4-benzothiadiazine1,1-dioxide
- HydroflumethiazideQ: What is
- 1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1λ
- hydroflumethizide
- Hudroflumethiazide
- 6-(trifluoroMethyl)-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonaMide 1,1-dioxide
- elodrin
- HYDROFLUMETHIAZIDE USP/EP/BP
- 1,1-DIOXO-6-(TRIFLUOROMETHYL)-1,2,3,4-TETRAHYDRO-1LAMBDA6,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE
- di-adenil
- dihydroflumethazide
- Hydroflumethiazide Q: What are the applications of
- Hydroflumethiazide (200 mg)
- 3,4-dihydro-7-sulfamyl-6-trifluoromethyl-2h-1,2,4-benzothiadiazine1,1-dioxid
- 3,4-dihydro-6-trifluoromethyl-7-sulfamoylbenzo-1,2,4-thiadiazine1,1-dioxide
- HYDROFLUMETHIAZIDE,USP
- HYDROFLUMETHIAZIDE
- 3,4-dihydro-6-trifluoromethyl-2h-1,2,4-benzothiadiazine-7-sulfonamide1,1-dio
- Ademil
- River
- Hydroflumethiazide Q: What is the storage condition of
- trifluoromethylhydrazide
- 1,1-DIOXO-6-(TRIFLUOROMETHYL)-1,2,3,4-TETRAHYDRO-1L-6-2-4-BENZATHIADIAZINE-7-SULFONAMIDE
- ,2,4-benzothiadiazine-7-sulfonamide
- 3,4-DIHYDRO-6-(TRIFLUOROMETHYL)-2H-1,2,4-BENZOTHIADIAZINE-7-SULPHONAMIDE-1,1-DIOXIDE
- 4-benzothiadiazine-7-sulfonamide,3,4-dihydro-6-(trifluoromethyl)-,1,1-2h-2
- naciex(glaxo)
- See more synonyms
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Found 11 products.
Hydroflumethiazide
CAS:Sulfonamides used as drugsFormula:C8H8F3N3O4S2Color and Shape:Off-White White Crystalline PowderMolecular weight:331.296-(Trifluoromethyl)-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide
CAS:Formula:C8H8F3N3O4S2Purity:98%Color and Shape:SolidMolecular weight:331.2920Hydroflumethiazide
CAS:Formula:C8H8F3N3O4S2Color and Shape:White To Off-White SolidMolecular weight:331.28Hydroflumethiazide-15N2-13C-d2
CAS:Formula:C713CH6D2F3N15N2O4S2Color and Shape:White To Off-White SolidMolecular weight:336.273,4-Dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulphonamide 1,1-dioxide
CAS:<p>3,4-Dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulphonamide 1,1-dioxide</p>Formula:C8H8F3N3O4S2Purity:95%Color and Shape: white to off-white. crystals or powderMolecular weight:331.29202g/molHydroflumethiazide
CAS:Controlled Product<p>Applications Antihypertensive; diuretic.<br>References Piala, J.J., et al.: J. Pharmacol. Exp. Ther., 134, 273 (1961), Orzech, C.E., et al.: Anal. Profiles Drug Subs., 7, 297 (1978),<br></p>Formula:C8H8F3N3O4S2Color and Shape:NeatMolecular weight:331.29Hydroflumethiazide
CAS:<p>Hydroflumethiazide is a diuretic drug that is used to treat high blood pressure, heart failure, and edema. It decreases the production of aqueous humor by the eye, thereby decreasing intraocular pressure. Hydroflumethiazide also inhibits sodium reabsorption in the loop of Henle and helps to control hypertension. The drug increases renal excretion of water and electrolytes, which can lead to dehydration. Hydroflumethiazide has been shown to have an adverse effect on cardiovascular function due to its ability to inhibit ATP channels in cardiac cells and interfere with glomerular filtration rate (GFR). It has also been found to increase matrix metalloproteinases (MMP) activity in inflammatory bowel disease patients.</p>Formula:C8H8F3N3O4S2Purity:Min. 95%Molecular weight:331.29 g/molHydroflumethiazide
CAS:<p>Hydroflumethiazide is a thiazide diuretic. It has also shown the activity of anti-hypertensive.</p>Formula:C8H8F3N3O4S2Color and Shape:Crystals SolidMolecular weight:331.29
![6-(Trifluoromethyl)-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA003QYP.jpg&w=3840&q=75)
