CAS 13504-15-9

(16β)-17,21-Dihydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione

Description:

The chemical substance known as (16β)-17,21-Dihydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione, with the CAS number 13504-15-9, is a synthetic steroid that exhibits properties characteristic of corticosteroids. It features a steroid backbone with multiple hydroxyl groups, which contribute to its biological activity, particularly in modulating inflammation and immune responses. The presence of the 16-methyl group and the specific configuration at the 16β position are significant for its pharmacological effects. This compound is often studied for its potential therapeutic applications, including anti-inflammatory and immunosuppressive effects. Its structural modifications compared to natural corticosteroids may influence its potency, duration of action, and side effect profile. As with many steroids, it is important to consider its solubility, stability, and metabolic pathways when evaluating its use in clinical settings. Overall, this compound represents a class of medications that can be critical in managing various medical conditions, particularly those involving the immune system and inflammation.

Formula: C₂₂H₂₈O₄

InChI: InChI=1S/C22H28O4/c1-13-10-18-16-5-4-14-11-15(24)6-8-20(14,2)17(16)7-9-21(18,3)22(13,26)19(25)12-23/h6-8,11,13,16,18,23,26H,4-5,9-10,12H2,1-3H3/t13-,16+,18-,20-,21-,22-/m0/s1

InChI key: InChIKey=ZYTXTXAMMDTYDQ-AKXKBWEISA-N

SMILES: C[C@@]12[C@]([C@]3(C(=CC1)[C@]4(C)C(CC3)=CC(=O)C=C4)[H])(C[C@H](C)[C@@]2(C(CO)=O)O)[H]

Synonyms:

• (16Beta)-17,21-Dihydroxy-16-Methylpregna-1,4,9(11)-Triene-3,20-Dione
• (16β)-17,21-Dihydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione
• 17,21-Dihydroxy-16beta-methylpregna-1,4,9(11)-triene-3,20-dione
• Pregna-1,4,9(11)-triene-3,20-dione, 17,21-dihydroxy-16-methyl-, (16β)-
• Pregna-1,4,9(11)-triene-3,20-dione, 17,21-dihydroxy-16β-methyl-

(8S,10S,13S,14S,16S,17R)-17-Hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one (Betamethasone Impurity)

CAS: 13504-15-9

(8S,10S,13S,14S,16S,17R)-17-Hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one (Betamethasone Impurity)

Purity: 98%

Ref: 54-OR1039864

Betamethasone EP Impurity C

CAS: 13504-15-9

Formula: C₂₂H₂₈O₄

Color and Shape: Off-White Solid

Molecular weight: 356.46

Ref: 4Z-B-065015

(16β)-17,21-Dihydroxy-16β-methyl-pregna-1,4,9(11)-triene-3,20-dione

Controlled Product

CAS: 13504-15-9

Impurity Betamethasone EP Impurity C
Applications (16β)-17,21-Dihydroxy-16β-methyl-pregna-1,4,9(11)-triene-3,20-dione (Betamethasone EP Impurity C) is used in biological studies to perform preclinical characterization of VBP15, a novel anti-inflammatory delta 9,11 steroid. This compound is also used in analytical studies to determine the stability from reversed-phase high performance liquid chromatography (RP-HPLC) to separate low levels of dexamethasone and other related compounds from betametasone, which is an active pharmaceutical ingredient.
References Reeves, E.K.M., et al.: Bioorg., Med. Chem., 21, 2241 (2013), Xiong, Y., et al.: J. Pharm. Biomed. Anal., 49, 646 (2009)

Formula: C₂₂H₂₈O₄

Color and Shape: Neat

Molecular weight: 356.46

Ref: TR-D453255

Betamethasone EP Impurity C

CAS: 13504-15-9

Formula: C₂₂H₂₈O₄

Molecular weight: 356.5

Ref: ST-EA-CP-B25003

17,21Dihydroxy-16β-methylpregna-1,4,9(11)-triene-3,20-dione

Controlled Product

CAS: 13504-15-9

Please enquire for more information about 17,21Dihydroxy-16beta-methylpregna-1,4,9(11)-triene-3,20-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₂₂H₂₈O₄

Purity: Min. 95%

Molecular weight: 356.46 g/mol

Ref: 3D-FD45457