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CAS 135042-12-5

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N-t-BOC-cis-4-hydroxy-D-proline

Description:
N-t-BOC-cis-4-hydroxy-D-proline is a derivative of proline, an amino acid that plays a crucial role in protein synthesis. This compound features a tert-butyloxycarbonyl (t-BOC) protecting group, which is commonly used in peptide synthesis to protect the amino group from unwanted reactions. The "cis" configuration indicates the spatial arrangement of the hydroxyl group relative to the proline backbone, which can influence the compound's biological activity and interactions. The presence of the hydroxyl group at the 4-position enhances its potential for hydrogen bonding, making it useful in various biochemical applications. This compound is often utilized in the synthesis of peptides and other bioactive molecules, particularly in the development of pharmaceuticals. Its unique structural characteristics contribute to its stability and reactivity, making it a valuable intermediate in organic synthesis. As with many chemical substances, proper handling and storage are essential to maintain its integrity and ensure safety during use.
Formula:C10H17NO5
InChI:InChI=1/C10H17NO5/c1-10(2,3)16-9(15)11-5-6(12)4-7(11)8(13)14/h6-7,12H,4-5H2,1-3H3,(H,13,14)/t6-,7-/m1/s1
SMILES:CC(C)(C)OC(=O)N1C[C@@H](C[C@@H]1C(=O)O)O
Synonyms:
  • (4R)-1-(tert-butoxycarbonyl)-4-hydroxy-D-proline
  • Boc-cis-4-Hydroxy-D-proline
  • (2R,4R)-N-Boc-4-Hydroxypyrrolidine-2-Carboxylic Acid
  • cis-Boc-D-Hyp-OH
  • Boc-cis-D-Hyp-OH
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