The chemical substance with the name "N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-D-ornithinamide" and CAS number 1350456-66-4 is a complex organic compound characterized by its multi-functional structure. It features a pyrrole-derived moiety, which contributes to its potential biological activity, and includes various functional groups such as amides and carbonyls that may influence its solubility and reactivity. The presence of a nitrophenoxy group suggests potential applications in medicinal chemistry, possibly as a prodrug or in targeted drug delivery systems. The compound's stereochemistry, indicated by the presence of L-valyl and D-ornithine residues, may play a crucial role in its interaction with biological targets, such as enzymes or receptors. Overall, this compound's intricate structure and diverse functional groups make it a candidate for further investigation in pharmaceutical research, particularly in the development of novel therapeutic agents.

N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-D-ornithinamide

1350456-66-4: The chemical substance with the name "N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-D-ornithinamide" and CAS number 1350456-66-4 is a complex organic compound characterized by its multi-functional structure. It features a pyrrole-derived moiety, which contributes to its potential biological activity, and includes various functional groups such as amides and carbonyls that may influence its solubility and reactivity. The presence of a nitrophenoxy group suggests potential applications in medicinal chemistry, possibly as a prodrug or in targeted drug delivery systems. The compound's stereochemistry, indicated by the presence of L-valyl and D-ornithine residues, may play a crucial role in its interaction with biological targets, such as enzymes or receptors. Overall, this compound's intricate structure and diverse functional groups make it a candidate for further investigation in pharmaceutical research, particularly in the development of novel therapeutic agents.

MC-Val-D-Cit-PAB-PNP, a cleavable peptide linker, facilitates the production of antibody-drug conjugates (ADCs) by featuring a maleimidocaproyl (Mc) group for antibody conjugation and a p-nitrophenol (PNP) group to connect to antitumor compounds.

CAS 1350456-66-4

N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-D-ornithinamide

MC-Val-D-Cit-PAB-PNP

Ref: TM-T87900