CAS 135046-48-9
:Clopidogrel hydrogen sulfate
Description:
Clopidogrel hydrogen sulfate is a pharmaceutical compound primarily used as an antiplatelet agent to prevent blood clots in patients at risk of cardiovascular events. It is a prodrug that requires metabolic activation in the liver to exert its therapeutic effects. The substance is characterized by its ability to irreversibly inhibit the P2Y12 receptor on platelets, thereby reducing platelet aggregation. Clopidogrel hydrogen sulfate is typically administered orally and is known for its relatively low bioavailability, necessitating consideration of factors such as food interactions and genetic variations in metabolism among patients. The compound is often prescribed in combination with other medications, such as aspirin, to enhance its efficacy in preventing thrombotic events. In terms of safety, it may have side effects, including bleeding risks, and requires monitoring in certain populations. Its chemical structure includes a thiophenyl group, contributing to its pharmacological properties. Overall, Clopidogrel hydrogen sulfate plays a crucial role in managing cardiovascular diseases, highlighting the importance of antiplatelet therapy in clinical practice.
Formula:C15H16ClNO6S2
InChI:InChI=1/C15H14ClNO2S.H2O4S/c16-12-4-2-1-3-11(12)14(15(18)19)17-7-5-13-10(9-17)6-8-20-13;1-5(2,3)4/h1-4,6,8,14H,5,7,9H2,(H,18,19);(H2,1,2,3,4)/t14-;/m0./s1
InChI key:InChIKey=FDEODCTUSIWGLK-UHFFFAOYSA-N
SMILES:C(C(OC)=O)(N1CC2=C(CC1)SC=C2)C3=C(Cl)C=CC=C3.S(=O)(=O)(O)O
Synonyms:- (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoic acid sulfate (1:1)
- (RS)-Clopidogrel bisulfate
- (±)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyrid-5-yl)acetate hydrogen sulfate salt (1:1)
- Clopidogerl Bisulfate
- Clopidogrel Bisulfate
- Clopidogrel Bisulfate I
- Clopidogrel Bisulfate II
- Clopidogrel Bisulfate, FormI/FormII
- Clopidogrel Hydrogen Sulphate
- Clopidogrel Hydrogensulfate
- Clopidogrel Sulphate
- Clopidogrel bisulphate
- Clopidogrel bisulphate Ⅰ/Ⅱ
- Clopidogrel sulfate
- Methyl (+)-(S)-A-(2-Chlorophenyl)-6,7-Dihydrothieno[3,2-C]Pyridine-5(4H)Acetate, Hydrogen Sulfate Salt
- Methyl 2-(2-Chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate hydrogen sulfate
- Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, methyl ester, sulfate (1:1)
- PLAVIX
- CLOPIDOGREL HYDROGEN SULFATE
- SR-25990, Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate hydrogen sulfate
- (2-chlorophenyl)-6,7╟dihydrothieno[3,2-c]pyridine-5-(4h)-acetic acid methyl ester sulfate
- Methyl (S)-alpha-(2-Chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetate hydrogen sulfate
- Clopidogrel hydrogen sulfate
- SR-25990C
- See more synonyms
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Found 12 products.
(±) Clopidogrel hydrogen sulfate
CAS:<p>(±) Clopidogrel hydrogen sulfate (Iscover) , an antiplatelet agent pharmacologically and structurally analogous to ticlopidine, is used to inhibit blood clots</p>Formula:C16H16ClNO2S·H2SO4Purity:98.67% - 99.04%Color and Shape:Colorless To Light Yellow LiquidMolecular weight:419.9Clopidogrel bisulfate
CAS:Formula:C16H18ClNO6S2Purity:99%Color and Shape:SolidMolecular weight:419.9002(±) Clopidogrel hydrogen sulfate
CAS:<p>(±) Clopidogrel hydrogen sulfate</p>Purity:≥98%Molecular weight:419.9g/molrac-Clopidogrel-d3 Sulfate
CAS:Formula:C16H13D3ClNO2S·H2O4SColor and Shape:White To Off-White SolidMolecular weight:324.84 98.07rac Clopidogrel Hydrogen Sulfate-d9 (Major)
CAS:Controlled Product<p>Applications Labelled Clopidogrel, an antithrombotic.<br>References Mills, D.C.B., et al.: Arterioscler. Thromb., 12, 430 (1992), Feuerstein, G., et al.: Exp. Opin. Invest. Drugs, 4, 425 (1995)<br></p>Formula:C16H9D9ClNO6S2Color and Shape:NeatMolecular weight:428.96rac-Clopidogrel-d3 Hydrogen Sulfate
CAS:Controlled Product<p>Applications rac-Clopidogrel-d3 Hydrogen Sulfate is the labeled analogue of rac-Clopidogrel Hydrogen Sulfate (C587248), which is used in the synthesis of Clopidogrel derivatives as platelet aggregation inhibitors.<br>References Chen, J., et. al.: Hecheng Huaxue, 18, 586 (2010)<br></p>Formula:C16H15D3ClNO6S2Color and Shape:NeatMolecular weight:422.92rac-Clopidogrel Hydrogen Sulfate
CAS:Controlled Product<p>Applications rac-Clopidogrel Hydrogen Sulfate is used in the synthesis of Clopidogrel derivatives as platelet aggregation inhibitors.<br>References Chen, J., et. al.: Hecheng Huaxue, 18, 586 (2010); Defreyn, G. et al.: Thromb. Haemo., 65, 186 (1991);<br></p>Formula:C16H16ClNO2S·H2O4SColor and Shape:Off-WhiteMolecular weight:419.90Clopidogrel bisulfate
CAS:<p>Clopidogrel is a potent inhibitor of the platelet aggregation. It reduces blood clotting by inhibiting the ADP receptor on the surface of platelets, thereby inhibiting the aggregation and adhesion of platelets. Clopidogrel has been shown to be effective in preventing thrombosis, myocardial infarction (heart attack), and stroke. Clopidogrel inhibits the activity of cytochrome P450 3A4 (CYP3A4) and p2Y 12 receptors. Clopidogrel has been shown to have synergic effects with nonsteroidal anti-inflammatory drugs (NSAIDs). The polymorphic nature of Clopidogrel can be monitored using a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for quantification in biological samples such as human serum and plasma.</p>Formula:C16H16ClNO2S·H2O4SPurity:Min. 95%Molecular weight:419.9 g/mol
