CAS 135046-48-9: Clopidogrel hydrogen sulfate
Description:Clopidogrel hydrogen sulfate is a pharmaceutical compound primarily used as an antiplatelet agent to prevent blood clots in patients at risk of cardiovascular events. It is a prodrug that requires metabolic activation in the liver to exert its therapeutic effects. The substance is characterized by its ability to irreversibly inhibit the P2Y12 receptor on platelets, thereby reducing platelet aggregation. Clopidogrel hydrogen sulfate is typically administered orally and is known for its relatively low bioavailability, necessitating consideration of factors such as food interactions and genetic variations in metabolism among patients. The compound is often prescribed in combination with other medications, such as aspirin, to enhance its efficacy in preventing thrombotic events. In terms of safety, it may have side effects, including bleeding risks, and requires monitoring in certain populations. Its chemical structure includes a thiophenyl group, contributing to its pharmacological properties. Overall, Clopidogrel hydrogen sulfate plays a crucial role in managing cardiovascular diseases, highlighting the importance of antiplatelet therapy in clinical practice.
Formula:C15H18ClNO6S2
InChI:InChI=1S/C16H16ClNO2S.H2O4S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14;1-5(2,3)4/h2-5,7,9,15H,6,8,10H2,1H3;(H2,1,2,3,4)
InChI key:InChIKey=FDEODCTUSIWGLK-UHFFFAOYSA-N
SMILES:O=C(OC)C(C=1C=CC=CC1Cl)N2CC=3C=CSC3CC2.O=S(=O)(O)O
- Synonyms:
- (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoic acid sulfate (1:1)
- (RS)-Clopidogrel bisulfate
- (±)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyrid-5-yl)acetate hydrogen sulfate salt (1:1)
- Clopidogerl Bisulfate
- Clopidogrel Bisulfate
- Clopidogrel Bisulfate I
- Clopidogrel Bisulfate II
- Clopidogrel Bisulfate, FormI/FormII
- Clopidogrel Hydrogen Sulphate
- Clopidogrel Hydrogensulfate
- See more synonyms
- Clopidogrel Sulphate
- Clopidogrel bisulphate
- Clopidogrel bisulphate Ⅰ/Ⅱ
- Clopidogrel sulfate
- Methyl (+)-(S)-A-(2-Chlorophenyl)-6,7-Dihydrothieno[3,2-C]Pyridine-5(4H)Acetate, Hydrogen Sulfate Salt
- Methyl 2-(2-Chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate hydrogen sulfate
- Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, methyl ester, sulfate (1:1)
