Tubacin, identified by the CAS number 1350555-93-9, is a chemical compound that has garnered attention primarily for its role as a selective inhibitor of the enzyme HDAC6 (histone deacetylase 6). This enzyme is involved in various cellular processes, including the regulation of protein acetylation, which plays a crucial role in gene expression and cellular signaling. Tubacin's inhibition of HDAC6 has implications in cancer research, neurodegenerative diseases, and other conditions where protein misfolding and aggregation are prevalent. The compound is characterized by its ability to enhance the acetylation of tubulin, leading to altered cellular dynamics and potentially promoting neuroprotective effects. Additionally, Tubacin's selectivity for HDAC6 over other HDAC isoforms makes it a valuable tool in studying the specific functions of this enzyme in various biological contexts. As with many research chemicals, its use is primarily confined to laboratory settings, and further studies are necessary to fully elucidate its therapeutic potential and safety profile.

Tubacin

1350555-93-9: Tubacin, identified by the CAS number 1350555-93-9, is a chemical compound that has garnered attention primarily for its role as a selective inhibitor of the enzyme HDAC6 (histone deacetylase 6). This enzyme is involved in various cellular processes, including the regulation of protein acetylation, which plays a crucial role in gene expression and cellular signaling. Tubacin's inhibition of HDAC6 has implications in cancer research, neurodegenerative diseases, and other conditions where protein misfolding and aggregation are prevalent. The compound is characterized by its ability to enhance the acetylation of tubulin, leading to altered cellular dynamics and potentially promoting neuroprotective effects. Additionally, Tubacin's selectivity for HDAC6 over other HDAC isoforms makes it a valuable tool in studying the specific functions of this enzyme in various biological contexts. As with many research chemicals, its use is primarily confined to laboratory settings, and further studies are necessary to fully elucidate its therapeutic potential and safety profile.

<p>Tubacin is a natural compound that has been found to inhibit the histone deacetylase (HDAC) enzyme. Tubacin has shown significant cytotoxicity against cancer cells and other cells in vitro. It inhibits HDAC and prevents the acetylation of histones, which are proteins that package DNA strands into chromosomes. This inhibition leads to increased gene expression and cell death. Tubacin is not toxic to normal cells, but it does cause oxidative injury to neurons.</p>

CAS 1350555-93-9

Tubacin

Tubacin

Ref: 3D-AEC55593