CAS 1350636-82-6
:Lefamulin acetate
Description:
Lefamulin acetate is a semi-synthetic antibiotic belonging to the pleuromutilin class, primarily used for the treatment of bacterial infections, particularly those caused by Gram-positive bacteria. It functions by inhibiting protein synthesis through binding to the peptidyl transferase center of the bacterial ribosome, thereby preventing the growth and reproduction of bacteria. The acetate form of lefamulin enhances its solubility and bioavailability. This compound is characterized by its broad-spectrum activity, making it effective against various pathogens, including those resistant to other antibiotics. Lefamulin acetate is typically administered via intravenous or oral routes, depending on the formulation. Its pharmacokinetic properties include a favorable distribution profile and a relatively long half-life, allowing for convenient dosing regimens. As with any antibiotic, the potential for resistance development is a concern, necessitating careful use in clinical settings. Overall, lefamulin acetate represents a significant advancement in antibiotic therapy, particularly in the context of rising antibiotic resistance.
Formula:C30H49NO7S
InChI:InChI=1S/C28H45NO5S.C2H4O2/c1-6-26(4)14-22(34-23(32)15-35-21-8-7-18(29)13-20(21)31)27(5)16(2)9-11-28(17(3)25(26)33)12-10-19(30)24(27)28;1-2(3)4/h6,16-18,20-22,24-25,31,33H,1,7-15,29H2,2-5H3;1H3,(H,3,4)/t16-,17+,18-,20-,21-,22-,24+,25+,26-,27+,28+;/m1./s1
InChI key:WSMXIQXWHPSVDE-ZPJPNJFZSA-N
SMILES:C[C@@H]1CC[C@@]23CCC(=O)[C@H]2[C@@]1([C@@H](C[C@@]([C@H]([C@@H]3C)O)(C)C=C)OC(=O)CS[C@@H]4CC[C@H](C[C@H]4O)N)C.CC(=O)O
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Lefamulin acetate
CAS:Lefamulin acetate, a novel antibiotic, treats human bacterial infections and CABP by inhibiting protein synthesis.Formula:C30H49NO7SPurity:99.87% - 99.93%Color and Shape:SolidMolecular weight:567.78Lefamulin acetate
CAS:(3aR,4R,5R,7S,8S,9R,9aS,12R)-8-Hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-(((1R,2R,4R)-4-amino-2-hydroxycyclohexyl)thio)acetate acetateFormula:C30H49NO7SPurity:97%Molecular weight:567.78Lefamulin acetate
CAS:Controlled ProductPlease enquire for more information about Lefamulin acetate including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C30H49NO7SPurity:Min. 95%Color and Shape:PowderMolecular weight:567.8 g/mol
