2,4,6-Tris(trifluoromethyl)benzoyl chloride is an organic compound characterized by its trifluoromethyl groups attached to a benzoyl chloride moiety. This compound features a benzene ring with three trifluoromethyl groups (-CF3) positioned at the 2, 4, and 6 positions, which significantly enhances its electron-withdrawing properties. The presence of the benzoyl chloride functional group (-C(=O)Cl) makes it a reactive acyl chloride, allowing it to participate in various chemical reactions, such as acylation and nucleophilic substitution. The trifluoromethyl groups contribute to the compound's lipophilicity and thermal stability, making it useful in synthetic organic chemistry, particularly in the development of pharmaceuticals and agrochemicals. Additionally, due to the strong electronegative nature of fluorine, this compound may exhibit unique reactivity patterns compared to its non-fluorinated counterparts. Safety precautions should be observed when handling this compound, as it may be corrosive and harmful upon exposure.

2,4,6-TRIS(TRIFLUOROMETHYL)BENZOYL CHLORIDE

135130-97-1: 2,4,6-Tris(trifluoromethyl)benzoyl chloride is an organic compound characterized by its trifluoromethyl groups attached to a benzoyl chloride moiety. This compound features a benzene ring with three trifluoromethyl groups (-CF3) positioned at the 2, 4, and 6 positions, which significantly enhances its electron-withdrawing properties. The presence of the benzoyl chloride functional group (-C(=O)Cl) makes it a reactive acyl chloride, allowing it to participate in various chemical reactions, such as acylation and nucleophilic substitution. The trifluoromethyl groups contribute to the compound's lipophilicity and thermal stability, making it useful in synthetic organic chemistry, particularly in the development of pharmaceuticals and agrochemicals. Additionally, due to the strong electronegative nature of fluorine, this compound may exhibit unique reactivity patterns compared to its non-fluorinated counterparts. Safety precautions should be observed when handling this compound, as it may be corrosive and harmful upon exposure.

<p>Applications 2,4,6-Tris(trifluoromethyl)benzoyl Chloride is an intermediate in the synthesis of 2,4,6-Tris(trifluoromethyl)aniline (T876695). 2,4,6-Tris(trifluoromethyl)aniline, is a Fluorinated substituents that have become valuable tool in medical chemistry. It can also be used for the preparation of azo dyes containing fluorine.<br>References Gandel'sman, L. Z., et al.: Ukrainskii Khimicheskii , 41, 61 (1975); Edelbach, B. L., et al.: Synthesis, 44, 3595 (2012)<br></p>

CAS 135130-97-1

2,4,6-TRIS(TRIFLUOROMETHYL)BENZOYL CHLORIDE

2,4,6-Tris(trifluoromethyl)benzoyl Chloride

Ref: TR-T897545