CAS 1351635-67-0
:ONO-4059
Description:
ONO-4059, also known by its chemical name, is a small molecule that functions primarily as a selective inhibitor of the enzyme Bruton's tyrosine kinase (BTK). This inhibition plays a crucial role in modulating B-cell receptor signaling, making ONO-4059 a candidate for therapeutic applications in various hematological malignancies and autoimmune diseases. The compound is characterized by its ability to interfere with B-cell activation and proliferation, which is significant in the context of diseases driven by aberrant B-cell activity. Its pharmacological profile suggests a favorable safety and efficacy balance, although specific clinical outcomes depend on ongoing research and trials. The compound's structure and mechanism of action contribute to its potential as a targeted therapy, highlighting the importance of BTK in the immune response. As with many investigational drugs, further studies are essential to fully elucidate its therapeutic potential and any associated side effects.
Formula:C25H24N6O3
Synonyms:- ON-0459 analog
- ONO-4059 analogue
- ON 0459 ANALOG;ON-0459 ANALOG
- 8H-Purin-8-one, 6-amino-7,9-dihydro-9-[(3S)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]-7-(4-phenoxyphenyl)-
- ONO-4059 (analog)
- ONO-4059 (ONO-WG-307)
- 6-AMINO-7-(4-PHENOXYPHENYL)-9-[(3S)-1-(PROP-2-ENOYL)PIPERIDIN-3-YL]PURIN-8-ONE
- 6-Amino-7,9-dihydro-9-[(3S)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]-7-(4-phenoxyphenyl)-8H-purin-8-one
- ONO-4059
- (R)-9-(1-acryloylpiperidin-3-yl)-6-amino-7-(4-phenoxyphenyl)-7H-purin-8(9H)-one
- CS-1629
- GS-4059
- ONO-4059 analog(GS-4059 analog)
- See more synonyms
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Found 3 products.
ONO-4059 analog
CAS:<p>ONO-4059 analog (ONO-WG-307)ue is an analogue of ONO-4059, which is a highly potent and selective oral BTK inhibitor with IC50 of 23.9 nM. Phase 1.</p>Formula:C25H24N6O3Purity:99.25%Color and Shape:SolidMolecular weight:456.5
