CAS 1351692-92-6
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Found 7 products.
Febuxostat Acyl Glucuronide
CAS:Formula:C22H24N2O9SColor and Shape:Pale Yellow SolidMolecular weight:492.50Febuxostat Acyl Glucuronide
CAS:Febuxostat acyl glucuronide, a febuxostat metabolite, forms through UGTs catalyzed glucuronidation.Formula:C22H24N2O9SColor and Shape:SolidMolecular weight:492.5Febuxostat-acyl-β-D-glucuronide
CAS:Febuxostat-acyl-β-D-glucuronidePurity:>96%Molecular weight:492.50g/molFebuxostat-acyl-β-D-glucuronide
CAS:Febuxostat is a drug that inhibits the enzyme xanthine oxidase, which is involved in the production of uric acid. The chronic use of this drug can lead to a decrease in serum uric acid levels, which is associated with lowering of blood pressure and prevention of kidney stones. Febuxostat has been shown to be effective in patients with polyarticular rheumatoid arthritis and allopurinol-induced gout. Side effects may include gastrointestinal discomfort, low dose-related hypertension, and cardiovascular complications. Febuxostat interacts with colchicine and other drugs that are metabolized through cytochrome P450 enzymes. This interaction may reduce the effectiveness of these drugs or increase their toxicity.Formula:C22H24N2O9SPurity:Min. 95%Color and Shape:PowderMolecular weight:492.5 g/molFebuxostat Acyl-β-D-glucuronide
CAS:<p>Applications A metabolite of Febuxostat (F229000), a novel nonpurine selective inhibitor of Xanthin Oxidase.<br>References Grabowski, B., et al.: J. Clin. Pharmacol., 51, 189 (2011); Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)<br></p>Formula:C22H24N2O9SColor and Shape:Off White PowderMolecular weight:492.50
