CAS 1351758-81-0

HG-10-102-01

CAS: 1351758-81-0

HG-10-102-01

Purity: ≥98%

Molecular weight: 377.83g/mol

Ref: 54-BUP09848

HG-10-102-01

CAS: 1351758-81-0

HG-10-102-01 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 of 20.3 nM).

Formula: C₁₇H₂₀ClN₅O₃

Purity: 99.59%

Color and Shape: Solid

Molecular weight: 377.83

Ref: TM-T7196

[4-[[5-Chloro-4-(methylamino)-2-pyrimidinyl]amino]-3-methoxyphenyl]-4-morpholinylmethanone

Controlled Product

CAS: 1351758-81-0

Formula: C₁₇H₂₀ClN₅O₃

Color and Shape: Neat

Molecular weight: 377.825

Ref: TR-C369030

[4-[[5-Chloro-4-(methylamino)-2-pyrimidinyl]amino]-3-methoxyphenyl]-4-morpholinylmethanone

CAS: 1351758-81-0

The drug, AZD1480, is a small molecule that binds to the toll-like receptor TLR4 and inhibits its function. This drug has been shown to inhibit microglia activation and reduce the production of pro-inflammatory cytokines in cell culture studies. The effects of AZD1480 are mediated by inhibiting autophagy, which is a process that cells use to degrade damaged proteins and organelles. This drug also inhibits the activity of polymerase chain reaction (PCR) enzymes, which prevents DNA replication in bacteria. The chemical structure of AZD1480 consists of a 4-morpholinyl group attached to a 4-[[5-chloro-4-(methylamino)-2-pyrimidinyl]amino]-3-methoxyphenyl group. It is classified as a synthetic compound with an unknown pharmacokinetic profile.

Formula: C₁₇H₂₀ClN₅O₃

Purity: Min. 95%

Molecular weight: 377.83 g/mol

Ref: 3D-BEC75881