CAS 1352085-46-1

3-allylnaloxone

Description:

3-Allylnaloxone is a synthetic opioid derivative that is structurally related to naloxone, a well-known opioid antagonist. This compound is characterized by the presence of an allyl group at the 3-position of the naloxone structure, which may influence its pharmacological properties. Like naloxone, 3-allylnaloxone is expected to interact with opioid receptors in the central nervous system, potentially exhibiting both agonistic and antagonistic effects depending on the context of its use. The compound is of interest in research related to pain management and opioid addiction treatment, as modifications to the naloxone structure can alter its efficacy and safety profile. Its chemical properties, such as solubility, stability, and reactivity, are influenced by the functional groups present in its structure. As with many synthetic opioids, understanding the pharmacokinetics and pharmacodynamics of 3-allylnaloxone is crucial for evaluating its therapeutic potential and safety in clinical applications. Further studies are necessary to fully elucidate its characteristics and potential uses in medicine.

3-O-Allyl Naloxone (4,5α-Epoxy-14-hydroxy-17-(prop-2-enyl)-3-(prop-2-enyloxy)morphinan-6-one)

CAS: 1352085-46-1

Alkaloids of opium and their derivatives, salts thereof, not elsewhere specified or included

Formula: C₂₂H₂₅NO₄

Color and Shape: White Solid

Molecular weight: 367.17836

Ref: 45-1A11190

4,5α-Epoxy-14-hydroxy-17-(prop-2-enyl)-3-(prop-2-enyloxy)morphinan-6-one (3-O-Allylnaloxone)

Controlled Product

CAS: 1352085-46-1

Color and Shape: Neat

Ref: 86-MM0272.10

3-Allyl Naloxone

Controlled Product

CAS: 1352085-46-1

Applications 3-Allyl Naloxone is an impurity of Naloxone (N285000), a specific opioid antagonist and narcotic antagonist.
References Jasinski, D.R., et al.: J. Pharmacol. Exp. Ther., 157, 420 (1967), McNicholas, L.F., et al.: Drugs, 27, 81 (1984), Hasson, M.M.A., et al.: Anal. Profiles Drug Subs., 14, 453 (1985), Stowe, C., et al.: Ann. Pharmacother., 27, 447 (1993),

Formula: C₂₂H₂₅NO₄

Color and Shape: Neat

Molecular weight: 367.44

Ref: TR-A558800

3-Allyl Naloxone (1 mg/ml in Acetonitrile)

Controlled Product

CAS: 1352085-46-1

Formula: C₂₂H₂₅NO₄

Color and Shape: Single Solution

Molecular weight: 367.44

Ref: TR-KIT2810

3-Allyl Naloxone-d5

Controlled Product

CAS: 1352085-46-1

Applications 3-Allyl Naloxone-d5 is labelled 3-Allyl Naloxone (A558800) which is an impurity of Naloxone (N285000), a specific opioid antagonist and narcotic antagonist.
References Jasinski, D.R., et al.: J. Pharmacol. Exp. Ther., 157, 420 (1967), McNicholas, L.F., et al.: Drugs, 27, 81 (1984), Hasson, M.M.A., et al.: Anal. Profiles Drug Subs., 14, 453 (1985), Stowe, C., et al.: Ann. Pharmacother., 27, 447 (1993),

Formula: C₂₂D₅H₂₀NO₄

Color and Shape: Neat

Molecular weight: 372.469

Ref: TR-A558802

3-Allyl Naloxone-d5 (1mg/ml in Acetonitrile)

Controlled Product

CAS: 1352085-46-1

Formula: C₂₂D₅H₂₀NO₄

Color and Shape: Single Solution

Molecular weight: 372.469

Ref: TR-KIT2815

Naloxone EP Impurity B

CAS: 1352085-46-1

Formula: C₂₂H₂₅NO₄

Molecular weight: 367.4

Ref: ST-EA-CP-N37003