CAS 13523-86-9: Pindolol

Description: Pindolol is a non-selective beta-adrenergic antagonist, commonly used in the treatment of hypertension and certain types of anxiety disorders. It is characterized by its ability to block both beta-1 and beta-2 adrenergic receptors, which helps to reduce heart rate and blood pressure. Pindolol has a moderate lipid solubility, allowing it to cross the blood-brain barrier, which can contribute to its anxiolytic effects. The chemical structure of pindolol includes a naphthalene ring, which is a key feature of its pharmacological activity. It is typically administered orally and has a relatively short half-life, necessitating multiple doses throughout the day for sustained therapeutic effects. Pindolol may also exhibit intrinsic sympathomimetic activity, meaning it can partially stimulate beta receptors while simultaneously blocking them, which can lead to a unique profile of cardiovascular effects. Common side effects may include fatigue, dizziness, and gastrointestinal disturbances. As with any medication, it is important for patients to consult healthcare professionals for personalized advice and monitoring.

Formula: C₁₄H₂₀N₂O₂

InChI: InChI=1S/C14H20N2O2/c1-10(2)16-8-11(17)9-18-14-5-3-4-13-12(14)6-7-15-13/h3-7,10-11,15-17H,8-9H2,1-2H3

InChI key: InChIKey=JZQKKSLKJUAGIC-UHFFFAOYSA-N

SMILES: OC(COC1=CC=CC=2NC=CC12)CNC(C)C

Synonyms:

• (.+-.)-4-[2-Hydroxy-3-(isopropylamino)propoxy]indole
• (1)-1-(1H-Indol-4-yloxy)-3-(isopropylamino)propan-2-ol
• (2R)-2-hydroxy-3-(1H-indol-4-yloxy)-N-(1-methylethyl)propan-1-aminium
• (2S)-2-hydroxy-3-(1H-indol-4-yloxy)-N-(1-methylethyl)propan-1-aminium
• (RS)-Pindolol
• 1-((1-Methylethyl)amino)-3-(4-indolyloxy)-2-propanol
• 1-(1H-Indol-4-yloxy)-3-((1-methylethyl)amino)-2-propanol
• 1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)propan-2-ol
• 1-(Indol-4-yloxy)-3-(isopropylamino)-2-propanol
• 2-Propanol, 1-(1H-indol-4-yloxy)-3-(1-methylethyl)amino-
• 2-Propanol, 1-(4-indolyloxy)-3-(isopropylamino)-
• 2-Propanol, 1-(indol-4-yloxy)-3-(isopropylamino)-, (+-)-
• 4-(2-Hydroxy-3-isopropylaminopropoxy)-indole
• 4-(3-(Isopropylamino)-2-hydroxypropoxy)indole
• <span class="text-smallcaps">DL</span>-4-[2-Hydroxy-3-(isopropylamino)propoxy]indole
• <span class="text-smallcaps">DL</span>-LB 46
• <span class="text-smallcaps">DL</span>-Pindolol
• Apo-pindol
• Betapindol
• Blocklin L
• Brn 1536506
• Calvisken
• Carvisken
• Ccris 9215
• DL-4-[2-Hydroxy-3-(isopropylamino)propoxy]indole
• DL-Pindolol
• Decreten
• Dl-Lb 46
• Durapindol
• Glauco-Visken
• Glauco-Viskin
• Hsdb 6539
• LB 46 (pharmaceutical)
• Lb 46
• N-[2-Hydroxy-3-(1H-indol-4-yloxy)propyl]-N-isopropylamine
• Pectobloc
• Pinbetol
• Pindolol [USAN:INN:BAN:JAN]
• Pindololum
• Pindololum [INN-Latin]
• Prinodolol
• Pynastin
• Unii-Bj4Hf6Iu1D
• Visken
• [2-Hydroxy-3-(1H-indol-4-yloxy)propyl](propan-2-yl)amine
• Pindolol
• (+-)-Pindolol
• 5-21-03-00017 (Beilstein Handbook Reference)
• Pindolol

Pindolol CRS

CAS: 13523-86-9

• Formula: C₁₄H₂₀N₂O₂
• Color and Shape: Powder
• Molecular weight: 248.3208

Pindolol

CAS: 13523-86-9

Cardiovascular drugs, not elsewhere specified or includ

• Formula: C₁₄H₂₀N₂O₂
• Color and Shape: White Off-White Powder
• Molecular weight: 248.15248

Pindolol

CAS: 13523-86-9

• Formula: C₁₄H₂₀N₂O₂
• Molecular weight: 248.32

Pindolol

CAS: 13523-86-9

• Formula: C₁₄H₂₀N₂O₂
• Molecular weight: 248.33

Pindolol

CAS: 13523-86-9

• Formula: C₁₄H₂₀N₂O₂
• Color and Shape: Neat
• Molecular weight: 248.32

Pindolol

CAS: 13523-86-9

• Formula: C₁₄H₂₀N₂O₂
• Color and Shape: Neat
• Molecular weight: 248.32

Pindolol

CAS: 13523-86-9

Applications Mixed β-adrenergic blocker and serotonin 5HT1A-receptor antagonist. Antihypertensive; antianginal; antiarrhythmic; antiglaucoma. Not a dangerous …

• Formula: C₁₄H₂₀N₂O₂
• Color and Shape: White To Off-White
• Molecular weight: 248.32

1-(1H-Indol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol

CAS: 13523-86-9

1-(1H-Indol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol is a 5-HT receptor agonist that is used in the treatment of depression. The …

• Formula: C₁₄H₂₀N₂O₂
• Purity: Min. 98 Area-%
• Color and Shape: White Off-White Powder
• Molecular weight: 248.32 g/mol