CAS 135248-89-4

L-Cysteine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-

Description:

L-Cysteine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]- is a derivative of the amino acid L-cysteine, which is known for its role in protein synthesis and as a precursor to the antioxidant glutathione. This compound features a protective fluorenylmethoxycarbonyl (Fmoc) group, commonly used in peptide synthesis to temporarily protect the amino group of amino acids. The presence of the Fmoc group enhances the stability and solubility of L-cysteine during chemical reactions, facilitating its incorporation into peptides. L-Cysteine itself is characterized by a thiol (-SH) group, which contributes to its reactivity and ability to form disulfide bonds, playing a crucial role in maintaining protein structure. The compound is typically utilized in biochemical research and peptide synthesis, where it can be deprotected to yield free L-cysteine for further applications. Overall, this substance combines the properties of L-cysteine with the advantages of the Fmoc protecting group, making it valuable in synthetic organic chemistry and biochemistry.

Formula: C₁₈H₁₇NO₄S

Synonyms:

• N-Fmoc-L-cysteine
• Fmoc-Cys-OH

(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-mercaptopropanoic acid

CAS: 135248-89-4

Formula: C₁₈H₁₇NO₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 343.3969

Ref: IN-DA007ZNA

Fmoc-cys-oh

CAS: 135248-89-4

Fmoc-cys-oh

Formula: C₁₈H₁₇NO₄S

Purity: 98%

Color and Shape: white solid

Molecular weight: 343.39687g/mol

Ref: 54-OR961460

Fmoc-L-cysteine

CAS: 135248-89-4

Fmoc-L-cysteine is a reactive thiol that can be used for the synthesis of peptides and proteins. Fmoc-L-cysteine is synthesized by hydrothiolation of L-cysteine with 3-mercaptopropionic acid, which leads to the formation of a disulfide bond. The reaction product is purified by column chromatography and analyzed by NMR spectroscopy. Fmoc-L-cysteine has been shown to have efficient prenylation activity in vitro and in cell culture experiments. It has also been shown to be an important amino acid for the formation of amyloid protein aggregates, as well as being involved with other helical peptides in plants. X-ray crystal structures have been determined for Fmoc-L-cysteine bound to monoclonal antibodies.

Formula: C₁₈H₁₇NO₄S

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 343.4 g/mol

Ref: 3D-FF49786

(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-mercaptopropanoic acid

CAS: 135248-89-4

Formula: C₁₈H₁₇NO₄S

Purity: 97%

Color and Shape: Solid

Molecular weight: 343.4

Ref: 10-F215116

FMOC-L-Cysteine extrapure, 95%

CAS: 135248-89-4

Formula: C₁₈H₁₇NO₄S

Molecular weight: 343.40

Ref: SR-65668

N-Fmoc-L-cysteine

Controlled Product

CAS: 135248-89-4

Applications N-Fmoc-L-cysteine is the N-Fmoc-protected form of L-Cysteine (C995000), a non-essential α-amino acid that is biosynthesized in humans. L-Cysteine is also a bicarbonate-sensitive endogenous excitotoxin in rats and possibly humans.
References Li, Q. et al.: Mat. Lett., 64, 614 (2010); Olney, J., et al.: Science, 4, 596 (1990)

Formula: C₁₈H₁₇NO₄S

Color and Shape: Neat

Molecular weight: 343.40

Ref: TR-F622805