CAS 1352570-51-4

2-(tert-Butyl)pyrimidine-5-boronic acid

Description:

2-(tert-Butyl)pyrimidine-5-boronic acid is an organoboron compound characterized by the presence of a pyrimidine ring substituted with a tert-butyl group and a boronic acid functional group. The tert-butyl group enhances the lipophilicity of the molecule, potentially influencing its solubility and reactivity in organic solvents. The boronic acid moiety is known for its ability to form reversible covalent bonds with diols, making it valuable in various applications, including medicinal chemistry and materials science. This compound may exhibit properties such as moderate stability under ambient conditions, but it can be sensitive to moisture due to the presence of the boronic acid group. Additionally, it may participate in Suzuki-Miyaura cross-coupling reactions, which are essential for the synthesis of complex organic molecules. Overall, 2-(tert-Butyl)pyrimidine-5-boronic acid serves as a versatile building block in organic synthesis and has potential applications in drug development and chemical biology.

Formula: C₈H₁₃BN₂O₂

Synonyms:

• Boronic acid, B-[2-(1,1-dimethylethyl)-5-pyrimidinyl]-
• 2-(tert-Butyl)pyrimidine-5-boronic acid
• (2-tert-butylpyrimidin-5-yl)boronic acid